N-Acetyl Linaclotide

About N-Acetyl Linaclotide

N-Acetyl Linaclotide is an impurity of Linaclotide carrying the CAS registry number 1422389-17-0. Its molecular formula is C61H81N15O22S6 and its molecular weight is 1568.8 g/mol. Common synonyms include AC-Cys1-Linaclotide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Linaclotide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Acetyl Linaclotide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linaclotide

View every impurity, metabolite and intermediate we list for Linaclotide.

Linaclotide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl Linaclotide
Catalogue No.	VQ-031557
CAS Number	1422389-17-0
IUPAC name	(2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-acetamido-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23,26,29,32,39,42,45,52-dodecazatetracyclo[22.22.4.216,33.07,11]dopentacontane-38-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Molecular formula	C₆₁H₈₁N₁₅O₂₂S₆
Molecular weight	1568.8 g/mol
Exact mass	1567.4005
Grade	Reference Standard
HSN code	38229090
InChIKey	MBPKFFIYHUXYJT-DHDUGXGCSA-N
SMILES	C[C@H]1C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)C(=O)N[C@@H](CSSC[C@@H](C(=O)N3)NC(=O)C)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)CC6=CC=C(C=C6)O)CCC(=O)O
PubChem CID	177831449

Physical properties
Physical form	Solid
LogP (XLogP3)	-4.3
H-bond donors / acceptors	19 / 28
TPSA	729 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl Linaclotide?

The CAS Registry Number of N-Acetyl Linaclotide is 1422389-17-0. It is also known as AC-Cys1-Linaclotide.

What is the molecular formula and molecular weight of N-Acetyl Linaclotide?

N-Acetyl Linaclotide has the molecular formula C61H81N15O22S6 and a molecular weight of 1568.8 g/mol.

What is N-Acetyl Linaclotide used for?

N-Acetyl Linaclotide is supplied as a characterised reference material related to Linaclotide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl Linaclotide can I order?

We supply N-Acetyl Linaclotide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl Linaclotide?

Yes. Every lot of N-Acetyl Linaclotide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl Linaclotide be shipped internationally?

Yes. We export N-Acetyl Linaclotide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.