2-Fluoro-4-nitrotoluene

About 2-Fluoro-4-nitrotoluene

2-Fluoro-4-nitrotoluene is an impurity of Apalutamide carrying the CAS registry number 1427-07-2. Its molecular formula is C7H6FNO2 and its molecular weight is 155.13 g/mol. The IUPAC name is 2-fluoro-1-methyl-4-nitrobenzene. It is also known as Benzene, 2-fluoro-1-methyl-4-nitro- or Toluene, 2-fluoro-4-nitro-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Apalutamide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apalutamide

View every impurity, metabolite and intermediate we list for Apalutamide.

Apalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Fluoro-4-nitrotoluene
Catalogue No.	VQ-044231
CAS Number	1427-07-2
IUPAC name	2-fluoro-1-methyl-4-nitrobenzene
Molecular formula	C₇H₆FNO₂
Molecular weight	155.13 g/mol
Exact mass	155.0383
Grade	Reference Standard
HSN code	38229090
InChIKey	WIQISTBTOQNVCE-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)[N+](=O)[O-])F
PubChem CID	74025

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 3
TPSA	45.8 Å²
Synonyms	Benzene, 2-fluoro-1-methyl-4-nitro-, Toluene, 2-fluoro-4-nitro-, 2-fluoro-1-methyl-4-nitro-benzene, 3-Fluoro-4-methylnitrobenzene, 1-Methyl-2-fluoro-4-nitrobenzene, 2-fluoro-1-methyl, 2-Fluor-4-nitro-toluol, 2-Fluoro-1-methyl-4-nitrobenzene #

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Danger

Hazard statements

H228Flammable solid
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P240, P241, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Fluoro-4-nitrotoluene?

The CAS Registry Number of 2-Fluoro-4-nitrotoluene is 1427-07-2. It is also known as Benzene, 2-fluoro-1-methyl-4-nitro-, Toluene, 2-fluoro-4-nitro-, 2-fluoro-1-methyl-4-nitro-benzene.

What is the molecular formula and molecular weight of 2-Fluoro-4-nitrotoluene?

2-Fluoro-4-nitrotoluene has the molecular formula C7H6FNO2 and a molecular weight of 155.13 g/mol. Its IUPAC name is 2-fluoro-1-methyl-4-nitrobenzene.

What is 2-Fluoro-4-nitrotoluene used for?

2-Fluoro-4-nitrotoluene is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Fluoro-4-nitrotoluene can I order?

We supply 2-Fluoro-4-nitrotoluene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Fluoro-4-nitrotoluene?

Yes. Every lot of 2-Fluoro-4-nitrotoluene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Fluoro-4-nitrotoluene be shipped internationally?

Yes. 2-Fluoro-4-nitrotoluene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.