Isosilybin A

Name: Isosilybin A
Brand: Vaqora Chemicals
SKU: VQ-037754

About Isosilybin A

Vaqora Chemicals supplies Isosilybin A, an impurity of Isosilybin registered under CAS number 142796-21-2. With the molecular formula C25H22O10, it has a molar mass of 482.4 g/mol. It is also known as Isosilibinin A or Silybin B2.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

This Isosilybin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isosilybin

View every impurity, metabolite and intermediate we list for Isosilybin.

Isosilybin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isosilybin A
Catalogue No.	VQ-037754
CAS Number	142796-21-2
IUPAC name	(2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula	C₂₅H₂₂O₁₀
Molecular weight	482.4 g/mol
Exact mass	482.1213
Grade	Reference Standard
HSN code	38229090
InChIKey	FDQAOULAVFHKBX-HKTJVKLFSA-N
SMILES	COC1=C(C=CC(=C1)[C@@H]2[C@H](OC3=C(O2)C=CC(=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	11059920

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	5 / 10
TPSA	155 Å²
Synonyms	Isosilibinin A, Silybin B2, 7-(4-bromobenzoyl)isosilybin A, Isosilybin AISB-A, Isosilybin A + B, Isosilybin A/(+)-Isosilybin A,Silybin b2

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isosilybin A?

The CAS Registry Number of Isosilybin A is 142796-21-2. It is also known as Isosilibinin A, Silybin B2, 7-(4-bromobenzoyl)isosilybin A.

What is the molecular formula and molecular weight of Isosilybin A?

Isosilybin A has the molecular formula C25H22O10 and a molecular weight of 482.4 g/mol. Its IUPAC name is (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one.

What is Isosilybin A used for?

Isosilybin A is supplied as a characterised reference material related to Isosilybin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isosilybin A can I order?

We supply Isosilybin A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isosilybin A?

Yes. Every lot of Isosilybin A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isosilybin A be shipped internationally?

Yes. Isosilybin A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.