Dextromethorphan EP Impurity B (Tartrate Salt) 143-98-6

About Dextromethorphan EP Impurity B (Tartrate Salt)

Dextromethorphan EP Impurity B (Tartrate Salt) is a pharmacopeial impurity of Dextromethorphan carrying the CAS registry number 143-98-6. The compound has the formula C21H29NO7, corresponding to a molecular weight of 407.5 g/mol. It is also known as ent-17-Methylmorphinan-3-ol Tartrate Salt or d-3-Hydroxy-N-methylmorphinan Tartrate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Dextromethorphan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Dextromethorphan EP Impurity B (Tartrate Salt) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dextromethorphan

View every impurity, metabolite and intermediate we list for Dextromethorphan.

Dextromethorphan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dextromethorphan EP Impurity B (Tartrate Salt)
Catalogue No.	VQ-006326
CAS Number	143-98-6
Other CAS	125-73-5
IUPAC name	(2R,3R)-2,3-dihydroxybutanedioic acid;(1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
Molecular formula	C₂₁H₂₉NO₇
Molecular weight	407.5 g/mol
Exact mass	407.1944
Grade	Reference Standard
HSN code	38229090
InChIKey	RWTWIZDKEIWLKQ-XCPWPWHNSA-N
SMILES	CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
PubChem CID	5484438

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 8
TPSA	139 Å²
Synonyms	ent-17-Methylmorphinan-3-ol Tartrate Salt, d-3-Hydroxy-N-methylmorphinan Tartrate, (9alpha,13alpha,14alpha)-17-Methyl-morphinan-3-ol (2R,3R)-2,3-Dihydroxybutanedioate, Dextrorphan Tartrate Salt, Dextrorphan D-Tartrate, Dextrorphan bitartrate, NIH 4591, Dextrorphan tartrate, Dextrophan tartrate, NIH-4591, 1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol tartrate, d-, Morphinan-3-ol, 17-methyl-, tartrate (1:1) (salt), (+)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dextromethorphan EP Impurity B (Tartrate Salt)?

The CAS Registry Number of Dextromethorphan EP Impurity B (Tartrate Salt) is 143-98-6. It is also known as ent-17-Methylmorphinan-3-ol Tartrate Salt, d-3-Hydroxy-N-methylmorphinan Tartrate, (9alpha,13alpha,14alpha)-17-Methyl-morphinan-3-ol (2R,3R)-2,3-Dihydroxybutanedioate.

What is the molecular formula and molecular weight of Dextromethorphan EP Impurity B (Tartrate Salt)?

Dextromethorphan EP Impurity B (Tartrate Salt) has the molecular formula C21H29NO7 and a molecular weight of 407.5 g/mol.

What is Dextromethorphan EP Impurity B (Tartrate Salt) used for?

Dextromethorphan EP Impurity B (Tartrate Salt) is supplied as a characterised reference material related to Dextromethorphan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dextromethorphan EP Impurity B (Tartrate Salt) can I order?

We supply Dextromethorphan EP Impurity B (Tartrate Salt) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dextromethorphan EP Impurity B (Tartrate Salt)?

Yes. Every lot of Dextromethorphan EP Impurity B (Tartrate Salt) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dextromethorphan EP Impurity B (Tartrate Salt) be shipped internationally?

Yes. Dextromethorphan EP Impurity B (Tartrate Salt) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.