Enoxolone EP Impurity A

About Enoxolone EP Impurity A

Enoxolone EP Impurity A is a pharmacopeial impurity of Enoxolone carrying the CAS registry number 1449-05-4. With the molecular formula C30H46O4, it has a molar mass of 470.7 g/mol. It is also known as Enoxolone EP Impurity A (Free Base) or 18alpha-Glycyrrhetinic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Enoxolone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Enoxolone EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Enoxolone

View every impurity, metabolite and intermediate we list for Enoxolone.

Enoxolone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Enoxolone EP Impurity A
Catalogue No.	VQ-027217
CAS Number	1449-05-4
IUPAC name	(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
Molecular formula	C₃₀H₄₆O₄
Molecular weight	470.7 g/mol
Exact mass	470.3396
Grade	Reference Standard
HSN code	38229090
InChIKey	MPDGHEJMBKOTSU-PMTKVOBESA-N
SMILES	C[C@]12CC[C@](C[C@@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
PubChem CID	73398

Physical properties
Physical form	Solid
LogP (XLogP3)	6.4
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	Enoxolone EP Impurity A (Free Base), 18alpha-Glycyrrhetinic acid, (18alpha)-3beta-Hydroxy-11-oxoolean-12-en-30-oic acid, 18alpha-GA, 18beta-GA, beta-Glycyrrhetinic acid, 18a-glycyrrhetinic acid, 18-Isoglycyrrhetinic acid, (3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid, 18a-Glycyrrhetic acid, 18-alpha-Glycyrrhetinic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Enoxolone EP Impurity A?

The CAS Registry Number of Enoxolone EP Impurity A is 1449-05-4. It is also known as Enoxolone EP Impurity A (Free Base), 18alpha-Glycyrrhetinic acid, (18alpha)-3beta-Hydroxy-11-oxoolean-12-en-30-oic acid.

What is the molecular formula and molecular weight of Enoxolone EP Impurity A?

Enoxolone EP Impurity A has the molecular formula C30H46O4 and a molecular weight of 470.7 g/mol. Its IUPAC name is (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid.

What is Enoxolone EP Impurity A used for?

Enoxolone EP Impurity A is supplied as a characterised reference material related to Enoxolone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Enoxolone EP Impurity A can I order?

We supply Enoxolone EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Enoxolone EP Impurity A?

Yes. Every lot of Enoxolone EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Enoxolone EP Impurity A be shipped internationally?

Yes. Enoxolone EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.