Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro… 145281-92-1

About Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine)

Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) is a metabolite or degradation product of Emtricitabine carrying the CAS registry number 145281-92-1. Its molecular formula is C8H9FN2O4S and its molecular weight is 248.23 g/mol. Systematically, it is named 5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione. It is also known as 5-Fluoro-3`-thia-2`,3`-dideoxyuridine or Emtricitabine FTU Impurity.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Emtricitabine, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Emtricitabine

View every impurity, metabolite and intermediate we list for Emtricitabine.

Emtricitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine)
Catalogue No.	VQ-022516
CAS Number	145281-92-1
IUPAC name	5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione
Molecular formula	C₈H₉FN₂O₄S
Molecular weight	248.23 g/mol
Exact mass	248.0267
Grade	Reference Standard
HSN code	38229090
InChIKey	KOGYOPLNKQJQFM-RITPCOANSA-N
SMILES	C1[C@@H](O[C@@H](S1)CO)N2C=C(C(=O)NC2=O)F
PubChem CID	455170

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	2 / 6
TPSA	104 Å²
Synonyms	5-Fluoro-3`-thia-2`,3`-dideoxyuridine, (2S-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione, Emtricitabine FTU Impurity, 2',3',5-Ftu, 2',3'-Dideoxy-5-fluoro-3'-thiauridine, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2S-cis)-, Oxathiolan, 5FU-(+)-beta, Emtricitabine Impurity 12, 5-fluoro-1-((2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione, (+)-(2S,5R)-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)uracil, Emtricitabine Impurity 11, (+)-(2S,5R)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]uracil

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine)?

The CAS Registry Number of Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) is 145281-92-1. It is also known as 5-Fluoro-3`-thia-2`,3`-dideoxyuridine, (2S-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione, Emtricitabine FTU Impurity.

What is the molecular formula and molecular weight of Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine)?

Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) has the molecular formula C8H9FN2O4S and a molecular weight of 248.23 g/mol. Its IUPAC name is 5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione.

What is Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) used for?

Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) is supplied as a characterised reference material related to Emtricitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) can I order?

We supply Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine)?

Yes. Every lot of Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) be shipped internationally?

Yes. We export Emtricitabine Impurity (2,3'-Dideoxy-5-Fluoro-3-Thiouridine) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.