2-epi-Emtricitabine

Name: 2-epi-Emtricitabine
Brand: Vaqora Chemicals
SKU: VQ-022514

About 2-epi-Emtricitabine

2-epi-Emtricitabine (CAS 145416-34-8) is an impurity of Emtricitabine offered by Vaqora Chemicals. Formula C8H10FN3O3S, molecular weight 247.25 g/mol. Systematically, it is named 4-amino-5-fluoro-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. It is also known as 2-epi-Emtricitabine, Emtricitabine 2-Epimer or Emtricitabine 2-Epimer.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Emtricitabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-epi-Emtricitabine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Emtricitabine

View every impurity, metabolite and intermediate we list for Emtricitabine.

Emtricitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-epi-Emtricitabine
Catalogue No.	VQ-022514
CAS Number	145416-34-8
IUPAC name	4-amino-5-fluoro-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Molecular formula	C₈H₁₀FN₃O₃S
Molecular weight	247.25 g/mol
Exact mass	247.0427
Grade	Reference Standard
HSN code	38229090
InChIKey	XQSPYNMVSIKCOC-WDSKDSINSA-N
SMILES	C1[C@H](O[C@@H](S1)CO)N2C=C(C(=NC2=O)N)F
PubChem CID	22858382

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	2 / 5
TPSA	113 Å²
Synonyms	2-epi-Emtricitabine, Emtricitabine 2-Epimer, Emtricitabine 2-Epimer, (2S,5S)-Emtricitabine, (-)-(2S,5S)-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cystosine, 4-amino-5-fluoro-1-((2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, Oxathiolan, 5FC-(-)-alpha, (-)-(2S,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine, 4-Amino-5-fluoro-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, Oxathiolan, 5FC-(-).a., 4-Amino-5-fluoro-1-[(2S,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, 4-Amino-5-fluoro-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H)-pyrimidone, (2S-trans)-4-Amino-5-fluoro-1-[2-(hydroxymethyl )-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-epi-Emtricitabine?

The CAS Registry Number of 2-epi-Emtricitabine is 145416-34-8. It is also known as 2-epi-Emtricitabine, Emtricitabine 2-Epimer, Emtricitabine 2-Epimer, (2S,5S)-Emtricitabine.

What is the molecular formula and molecular weight of 2-epi-Emtricitabine?

2-epi-Emtricitabine has the molecular formula C8H10FN3O3S and a molecular weight of 247.25 g/mol. Its IUPAC name is 4-amino-5-fluoro-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is 2-epi-Emtricitabine used for?

2-epi-Emtricitabine is supplied as a characterised reference material related to Emtricitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-epi-Emtricitabine can I order?

We supply 2-epi-Emtricitabine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-epi-Emtricitabine?

Yes. Every lot of 2-epi-Emtricitabine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-epi-Emtricitabine be shipped internationally?

Yes. We export 2-epi-Emtricitabine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.