Amiloride Impurity 1

Name: Amiloride Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-047381

About Amiloride Impurity 1

Amiloride Impurity 1 (CAS 1458-18-0) is an impurity of Amiloride offered by Vaqora Chemicals. Formula C6H5Cl2N3O2, molecular weight 222.03 g/mol. Its systematic (IUPAC) name is methyl 3-amino-5,6-dichloropyrazine-2-carboxylate. Common synonyms include Methyl 3-amino-5,6-dichloropyrazinoate and 3-Amino-5,.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Amiloride to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Amiloride

View every impurity, metabolite and intermediate we list for Amiloride.

Amiloride impurities

Specifications & identifiers

Chemical identifiers
Product name	Amiloride Impurity 1
Catalogue No.	VQ-047381
CAS Number	1458-18-0
IUPAC name	methyl 3-amino-5,6-dichloropyrazine-2-carboxylate
Molecular formula	C₆H₅Cl₂N₃O₂
Molecular weight	222.03 g/mol
Exact mass	220.9759
Grade	Reference Standard
HSN code	38229090
InChIKey	USYMCUGEGUFUBI-UHFFFAOYSA-N
SMILES	COC(=O)C1=C(N=C(C(=N1)Cl)Cl)N
PubChem CID	73828

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 5
TPSA	78.1 Å²
Synonyms	Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, 2-Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate, 3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester, Methyl 3-amino-5,6-dichloropyrazinoate, methyl 3-amino-5,6-dichloro-2-pyrazine-carboxylat, methyl 3-amino-5,6-dichloro-2-pyrazine carboxylate, 3-Amino-5,6-dichloro-pyrazine-2-carboxylic acid methyl ester, 3-Amino-5,6-dichloropyrazine-2-carboxylic acid methyl ester, 3-Amino-5,, methyl 3-amino-5,6-dichloropyrazinecarboxylate, 2-amino-5,6-dichloro-3-(methoxycarbonyl)pyrazine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amiloride Impurity 1?

The CAS Registry Number of Amiloride Impurity 1 is 1458-18-0. It is also known as Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, 2-Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate.

What is the molecular formula and molecular weight of Amiloride Impurity 1?

Amiloride Impurity 1 has the molecular formula C6H5Cl2N3O2 and a molecular weight of 222.03 g/mol. Its IUPAC name is methyl 3-amino-5,6-dichloropyrazine-2-carboxylate.

What is Amiloride Impurity 1 used for?

Amiloride Impurity 1 is supplied as a characterised reference material related to Amiloride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amiloride Impurity 1 can I order?

We supply Amiloride Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amiloride Impurity 1?

Yes. Every lot of Amiloride Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amiloride Impurity 1 be shipped internationally?

Yes. Amiloride Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.