1-Boc-L-tryptophan

About 1-Boc-L-tryptophan

1-Boc-L-tryptophan is a process intermediate or related compound of Tryptophan carrying the CAS registry number 146645-63-8. With the molecular formula C16H20N2O4, it has a molar mass of 304.34 g/mol. Systematically, it is named (2S)-2-amino-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid. It is also known as H-Trp(Boc)-OH or 1-(tert-butoxycarbonyl)-l-tryptophan.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Tryptophan, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Tryptophan

View every impurity, metabolite and intermediate we list for Tryptophan.

Tryptophan impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Boc-L-tryptophan
Catalogue No.	VQ-040555
CAS Number	146645-63-8
IUPAC name	(2S)-2-amino-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
Molecular formula	C₁₆H₂₀N₂O₄
Molecular weight	304.34 g/mol
Exact mass	304.1423
HSN code	2933
InChIKey	DYWUPCCKOVTCFZ-LBPRGKRZSA-N
SMILES	CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)C[C@@H](C(=O)O)N
PubChem CID	11833635

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	2 / 5
TPSA	94.6 Å²
Synonyms	H-Trp(Boc)-OH, 1-(tert-butoxycarbonyl)-l-tryptophan, 1-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan, 1-((1,1-Dimethylethoxy)carbonyl)-L-tryptophan, (S)-2-Amino-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid, L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-, N-in-Boc-L-tryptophan, L-Trp(Boc)-OH, Trp(Boc), H-Trp(Boc)-OH.nH2O, (2S)-2-amino-3-{, (2S)-2-amino-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Boc-L-tryptophan?

The CAS Registry Number of 1-Boc-L-tryptophan is 146645-63-8. It is also known as H-Trp(Boc)-OH, 1-(tert-butoxycarbonyl)-l-tryptophan, 1-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan.

What is the molecular formula and molecular weight of 1-Boc-L-tryptophan?

1-Boc-L-tryptophan has the molecular formula C16H20N2O4 and a molecular weight of 304.34 g/mol. Its IUPAC name is (2S)-2-amino-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid.

What is 1-Boc-L-tryptophan used for?

1-Boc-L-tryptophan is supplied as a characterised reference material related to Tryptophan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Boc-L-tryptophan can I order?

We supply 1-Boc-L-tryptophan, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Boc-L-tryptophan?

Yes. Every lot of 1-Boc-L-tryptophan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Boc-L-tryptophan be shipped internationally?

Yes. We export 1-Boc-L-tryptophan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.