Zopiclone EP impurity C

About Zopiclone EP impurity C

Zopiclone EP impurity C is a pharmacopeial impurity of Zopiclone carrying the CAS registry number 148891-53-6. Formula C11H7ClN4O, molecular weight 246.65 g/mol. The IUPAC name is 6-(5-chloro-2-pyridinyl)-7H-pyrrolo[3,4-b]pyrazin-5-one. Alternative names: Eszopiclone Impurity C and Zopiclone specified impurity C.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Zopiclone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Zopiclone

View every impurity, metabolite and intermediate we list for Zopiclone.

Zopiclone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Zopiclone EP impurity C
Catalogue No.	VQ-006781
CAS Number	148891-53-6
IUPAC name	6-(5-chloro-2-pyridinyl)-7H-pyrrolo[3,4-b]pyrazin-5-one
Molecular formula	C₁₁H₇ClN₄O
Molecular weight	246.65 g/mol
Exact mass	246.0308
Grade	Reference Standard
HSN code	38229090
InChIKey	ZWMNDASTKOEZHE-UHFFFAOYSA-N
SMILES	C1C2=NC=CN=C2C(=O)N1C3=NC=C(C=C3)Cl
PubChem CID	46782904

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 4
TPSA	59 Å²
Synonyms	6-(5-Chloro-2-pyridinyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloropyridin-2-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, Eszopiclone Impurity C, 5H-Pyrrolo(3,4-b)pyrazin-5-one, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-, 5H-Pyrrolo[3,4-b]pyrazin-5-one, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-, 6-(5-Chloropyridin-2-yl)-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-one, Zopiclone specified impurity C, RP 48497 (Eszopiclone Impurity C), 6-(5-chloropyridin-2-yl)-7H-pyrrolo[3,4-b]pyrazin-5-one, Zopiclone Impurity C, RP 48497, 6-(5-chloro-2-pyridyl)-7H-pyrrolo[3,4-b]pyrazin-5-one

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Zopiclone EP impurity C?

The CAS Registry Number of Zopiclone EP impurity C is 148891-53-6. It is also known as 6-(5-Chloro-2-pyridinyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloropyridin-2-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, Eszopiclone Impurity C.

What is the molecular formula and molecular weight of Zopiclone EP impurity C?

Zopiclone EP impurity C has the molecular formula C11H7ClN4O and a molecular weight of 246.65 g/mol. Its IUPAC name is 6-(5-chloro-2-pyridinyl)-7H-pyrrolo[3,4-b]pyrazin-5-one.

What is Zopiclone EP impurity C used for?

Zopiclone EP impurity C is supplied as a characterised reference material related to Zopiclone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Zopiclone EP impurity C can I order?

We supply Zopiclone EP impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Zopiclone EP impurity C?

Yes. Every lot of Zopiclone EP impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Zopiclone EP impurity C be shipped internationally?

Yes. Zopiclone EP impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.