D-Tryptophan Methyl Ester Hydrochloride

Name: D-Tryptophan Methyl Ester Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-034023

About D-Tryptophan Methyl Ester Hydrochloride

D-Tryptophan Methyl Ester Hydrochloride is an impurity of Tadalafil carrying the CAS registry number 14907-27-8. The compound has the formula C12H15ClN2O2, corresponding to a molecular weight of 254.71 g/mol. Alternative names: H-D-Trp-OMe.HCl and methyl D-tryptophanate hydrochloride.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Tadalafil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies D-Tryptophan Methyl Ester Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tadalafil

View every impurity, metabolite and intermediate we list for Tadalafil.

Tadalafil impurities

Specifications & identifiers

Chemical identifiers
Product name	D-Tryptophan Methyl Ester Hydrochloride
Catalogue No.	VQ-034023
CAS Number	14907-27-8
IUPAC name	methyl (2R)-2-amino-3-(1H-indol-3-yl)propanoate;hydrochloride
Molecular formula	C₁₂H₁₅ClN₂O₂
Molecular weight	254.71 g/mol
Exact mass	254.0822
Grade	Reference Standard
HSN code	38229090
InChIKey	XNFNGGQRDXFYMM-HNCPQSOCSA-N
SMILES	COC(=O)[C@@H](CC1=CNC2=CC=CC=C21)N.Cl
PubChem CID	11448200

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 3
TPSA	68.1 Å²
Synonyms	(2R)-Methyl 2-amino-3-(3H-indol-3-yl)propanoate hydrochloride, methyl (2R)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride, D-Tryptophan, methyl ester, hydrochloride (1:1), H-D-Trp-OMe.HCl, (R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride, methyl D-tryptophanate hydrochloride, H-D-Trp-OMe HCl, (R)-Tryptophane methyl ester hydrochloride, DTrp-OMe.HCl, Tadalafil Intermediate I

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of D-Tryptophan Methyl Ester Hydrochloride?

The CAS Registry Number of D-Tryptophan Methyl Ester Hydrochloride is 14907-27-8. It is also known as (2R)-Methyl 2-amino-3-(3H-indol-3-yl)propanoate hydrochloride, methyl (2R)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride, D-Tryptophan, methyl ester, hydrochloride (1:1).

What is the molecular formula and molecular weight of D-Tryptophan Methyl Ester Hydrochloride?

D-Tryptophan Methyl Ester Hydrochloride has the molecular formula C12H15ClN2O2 and a molecular weight of 254.71 g/mol.

What is D-Tryptophan Methyl Ester Hydrochloride used for?

D-Tryptophan Methyl Ester Hydrochloride is supplied as a characterised reference material related to Tadalafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of D-Tryptophan Methyl Ester Hydrochloride can I order?

We supply D-Tryptophan Methyl Ester Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with D-Tryptophan Methyl Ester Hydrochloride?

Yes. Every lot of D-Tryptophan Methyl Ester Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can D-Tryptophan Methyl Ester Hydrochloride be shipped internationally?

Yes. D-Tryptophan Methyl Ester Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.