Diclofenac-d4

Name: Diclofenac-d4
Brand: Vaqora Chemicals
SKU: VQ-030182

About Diclofenac-d4

Vaqora Chemicals supplies Diclofenac-d4, a stable isotope labelled analogue related to Diclofenac registered under CAS number 153466-65-0. With the molecular formula C14H11Cl2NO2, it has a molar mass of 300.2 g/mol. Its systematic (IUPAC) name is 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid. It is also known as Diclofenac-d4 (phenyl-d4-acetic) or TMIJ-0127.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Diclofenac and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Diclofenac-d4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Diclofenac

View every impurity, metabolite and intermediate we list for Diclofenac.

Diclofenac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diclofenac-d4
Catalogue No.	VQ-030182
CAS Number	153466-65-0
IUPAC name	2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid
Molecular formula	C₁₄H₁₁Cl₂NO₂
Molecular weight	300.2 g/mol
Exact mass	299.0418
Grade	Reference Standard
HSN code	38229090
InChIKey	DCOPUUMXTXDBNB-SCFZSLNVSA-N
SMILES	[2H]C1=C(C(=C(C(=C1[2H])CC(=O)O)NC2=C(C=CC=C2Cl)Cl)[2H])[2H]
PubChem CID	12877529

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	2-(2,3,4,5-Tetradeuterio-6-(2,6-dichloroanilino)phenyl)acetic acid, Diclofenac-d4 (phenyl-d4-acetic), TMIJ-0127, [2-(2,6-Dichloroanilino)(~2~H_4_)phenyl]acetic acid, 2-(2-((2,6-dichlorophenyl)amino)phenyl-3,4,5,6-d4)acetic acid

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diclofenac-d4?

The CAS Registry Number of Diclofenac-d4 is 153466-65-0. It is also known as 2-(2,3,4,5-Tetradeuterio-6-(2,6-dichloroanilino)phenyl)acetic acid, Diclofenac-d4 (phenyl-d4-acetic), TMIJ-0127.

What is the molecular formula and molecular weight of Diclofenac-d4?

Diclofenac-d4 has the molecular formula C14H11Cl2NO2 and a molecular weight of 300.2 g/mol. Its IUPAC name is 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid.

What is Diclofenac-d4 used for?

Diclofenac-d4 is supplied as a characterised reference material related to Diclofenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diclofenac-d4 can I order?

We supply Diclofenac-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diclofenac-d4?

Yes. Every lot of Diclofenac-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diclofenac-d4 be shipped internationally?

Yes. Diclofenac-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.