Gefitinib EP Impurity B

Name: Gefitinib EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006414

About Gefitinib EP Impurity B

Listed under CAS 1603814-04-5, Gefitinib EP Impurity B is a pharmacopeial impurity of Gefitinib available from Vaqora Chemicals, specified at 97.8% purity. With the molecular formula C22H24ClFN4O3, it has a molar mass of 446.9 g/mol. Systematically, it is named N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine. Common synonyms include Gefitinib EP Impurity B Hcl and Desfluoro gefitinib.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Gefitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Gefitinib EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Gefitinib EP Impurity B
Catalogue No.	VQ-006414
CAS Number	1603814-04-5
IUPAC name	N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Molecular formula	C₂₂H₂₄ClFN₄O₃
Molecular weight	446.9 g/mol
Exact mass	446.1521
Grade	Reference Standard
Purity / assay	97.8%
HSN code	38229090
InChIKey	WTDLLXPLBLPTEP-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)Cl)F)OCCCN4CCOCC4
PubChem CID	125323009

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 8
TPSA	68.7 Å²
Synonyms	N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib, 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib, Gefitinib EP Impurity B Hcl, Desfluoro gefitinib, 1603814-04-5 (free base), N-(4-chloro-3-fluoro-phenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gefitinib EP Impurity B?

The CAS Registry Number of Gefitinib EP Impurity B is 1603814-04-5. It is also known as N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib.

What is the molecular formula and molecular weight of Gefitinib EP Impurity B?

Gefitinib EP Impurity B has the molecular formula C22H24ClFN4O3 and a molecular weight of 446.9 g/mol. Its IUPAC name is N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine.

What is Gefitinib EP Impurity B used for?

Gefitinib EP Impurity B is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gefitinib EP Impurity B can I order?

We supply Gefitinib EP Impurity B in Reference Standard (97.8%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefitinib EP Impurity B?

Yes. Every lot of Gefitinib EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefitinib EP Impurity B be shipped internationally?

Yes. We export Gefitinib EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.