Binimetinib Amide Impurity

About Binimetinib Amide Impurity

Binimetinib Amide Impurity is an impurity of Binimetinib carrying the CAS registry number 1604812-70-5. Its molecular formula is C21H23BrF2N4O3 and its molecular weight is 497.3 g/mol. It is also known as Benzoimidazole derivative 1.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Binimetinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Binimetinib

View every impurity, metabolite and intermediate we list for Binimetinib.

Binimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Binimetinib Amide Impurity
Catalogue No.	VQ-004529
CAS Number	1604812-70-5
IUPAC name	6-(4-bromo-2-fluoroanilino)-7-fluoro-3-methyl-N-[2-[(2-methylpropan-2-yl)oxy]ethoxy]benzimidazole-5-carboxamide
Molecular formula	C₂₁H₂₃BrF₂N₄O₃
Molecular weight	497.3 g/mol
Exact mass	496.0922
Grade	Reference Standard
HSN code	38229090
InChIKey	MZHRFHRSYBBMON-UHFFFAOYSA-N
SMILES	CC(C)(C)OCCONC(=O)C1=CC2=C(C(=C1NC3=C(C=C(C=C3)Br)F)F)N=CN2C
PubChem CID	73775787

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 7
TPSA	77.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Binimetinib Amide Impurity?

The CAS Registry Number of Binimetinib Amide Impurity is 1604812-70-5. It is also known as Benzoimidazole derivative 1.

What is the molecular formula and molecular weight of Binimetinib Amide Impurity?

Binimetinib Amide Impurity has the molecular formula C21H23BrF2N4O3 and a molecular weight of 497.3 g/mol. Its IUPAC name is 6-(4-bromo-2-fluoroanilino)-7-fluoro-3-methyl-N-[2-[(2-methylpropan-2-yl)oxy]ethoxy]benzimidazole-5-carboxamide.

What is Binimetinib Amide Impurity used for?

Binimetinib Amide Impurity is supplied as a characterised reference material related to Binimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Binimetinib Amide Impurity can I order?

We supply Binimetinib Amide Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Binimetinib Amide Impurity?

Yes. Every lot of Binimetinib Amide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Binimetinib Amide Impurity be shipped internationally?

Yes. We export Binimetinib Amide Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.