3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric… 1620129-74-9

About 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid

3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid is an impurity of Sitagliptin carrying the CAS registry number 1620129-74-9. The compound has the formula C15H18F3NO4, corresponding to a molecular weight of 333.3 g/mol. Its systematic (IUPAC) name is 3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid. It is also known as N-Boc-(S)-2,4,5-trifluoro-b-homophenylalanine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Sitagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid
Catalogue No.	VQ-023769
CAS Number	1620129-74-9
IUPAC name	3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid
Molecular formula	C₁₅H₁₈F₃NO₄
Molecular weight	333.3 g/mol
Exact mass	333.1188
Grade	Reference Standard
HSN code	38229090
InChIKey	TUAXCHGULMWHIO-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)NC(CC1=CC(=C(C=C1F)F)F)CC(=O)O
PubChem CID	21911205

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 7
TPSA	75.6 Å²
Synonyms	3-{[(tert-butoxy)carbonyl]amino}-4-(2,4,5-trifluorophenyl)butanoic acid, Boc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid, 3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid, N-Boc-(S)-2,4,5-trifluoro-b-homophenylalanine, Boc-(R)-3-Amino-4-(2.4.5-trifluoromethyl) butyrate, Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid, 3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid, 3-tert-butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid, 3-tert-butoxycarbonylamino-4-(2,4,5-trifluorophenyl)butyric acid, 3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid, beta-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid?

The CAS Registry Number of 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid is 1620129-74-9. It is also known as 3-{[(tert-butoxy)carbonyl]amino}-4-(2,4,5-trifluorophenyl)butanoic acid, Boc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid, 3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid.

What is the molecular formula and molecular weight of 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid?

3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid has the molecular formula C15H18F3NO4 and a molecular weight of 333.3 g/mol. Its IUPAC name is 3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid.

What is 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid used for?

3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid can I order?

We supply 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid?

Yes. Every lot of 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid be shipped internationally?

Yes. We export 3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.