4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Ro… 162401-43-6

Name: 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
Brand: Vaqora Chemicals
SKU: VQ-033629

About 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast

4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast (CAS 162401-43-6) is an impurity of Roflumilast offered by Vaqora Chemicals. The compound has the formula C17H14Cl2F2N2O3, corresponding to a molecular weight of 403.2 g/mol. Its systematic (IUPAC) name is 4-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-3-(difluoromethoxy)benzamide. It is also known as last related substance A or RofluMilast IMp.A isoMer.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Roflumilast impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
Catalogue No.	VQ-033629
CAS Number	162401-43-6
IUPAC name	4-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-3-(difluoromethoxy)benzamide
Molecular formula	C₁₇H₁₄Cl₂F₂N₂O₃
Molecular weight	403.2 g/mol
Exact mass	402.035
Grade	Reference Standard
HSN code	38229090
InChIKey	VXNCCFGMEHFNBA-UHFFFAOYSA-N
SMILES	C1CC1COC2=C(C=C(C=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
PubChem CID	11269667

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	1 / 6
TPSA	60.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast?

The CAS Registry Number of 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast is 162401-43-6. It is also known as 4-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-3-(difluoromethoxy)benzamide, last related substance A, RofluMilast IMp.A isoMer.

What is the molecular formula and molecular weight of 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast?

4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast has the molecular formula C17H14Cl2F2N2O3 and a molecular weight of 403.2 g/mol. Its IUPAC name is 4-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-3-(difluoromethoxy)benzamide.

What is 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast used for?

4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast can I order?

We supply 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast?

Yes. Every lot of 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast be shipped internationally?

Yes. We export 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.