Methylprednisolone EP Impurity F

About Methylprednisolone EP Impurity F

Methylprednisolone EP Impurity F is a pharmacopeial impurity of Methylprednisolone carrying the CAS registry number 1625-39-4. The compound has the formula C22H32O5, corresponding to a molecular weight of 376.5 g/mol. Alternative names: 6-Alpha Methyl Hydrocortisone and Methylprednisolone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Methylprednisolone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methylprednisolone EP Impurity F is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Methylprednisolone

View every impurity, metabolite and intermediate we list for Methylprednisolone.

Methylprednisolone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Methylprednisolone EP Impurity F
Catalogue No.	VQ-023098
CAS Number	1625-39-4
IUPAC name	(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₂O₅
Molecular weight	376.5 g/mol
Exact mass	376.225
Grade	Reference Standard
HSN code	38229090
InChIKey	FQWLSWNUHFREIQ-PJHHCJLFSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)CC4)C)O)C)(C(=O)CO)O
PubChem CID	102147

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 5
TPSA	94.8 Å²
Synonyms	6-Alpha Methyl Hydrocortisone, Methylprednisolone, Methylprednisolone - Impurity F, 11beta,17,21-Trihydroxy-6alpha-methylpregn-4-ene-3,20-dione, 6alpha-methylhydrocortisone, 6alpha-methylcortisol, 6a-Methyl Hydrocortisone, 11-beta,17-alpha,21-Trihydroxy-6-alpha-methylpregn-4-ene-3,20-dione, 6alpha-Methyl Hydrocortisone, 6-Methyl Hydrocortisone, 6I+/--Methylhydrocortisone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methylprednisolone EP Impurity F?

The CAS Registry Number of Methylprednisolone EP Impurity F is 1625-39-4. It is also known as 6-Alpha Methyl Hydrocortisone, Methylprednisolone, Methylprednisolone - Impurity F.

What is the molecular formula and molecular weight of Methylprednisolone EP Impurity F?

Methylprednisolone EP Impurity F has the molecular formula C22H32O5 and a molecular weight of 376.5 g/mol. Its IUPAC name is (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is Methylprednisolone EP Impurity F used for?

Methylprednisolone EP Impurity F is supplied as a characterised reference material related to Methylprednisolone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methylprednisolone EP Impurity F can I order?

We supply Methylprednisolone EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methylprednisolone EP Impurity F?

Yes. Every lot of Methylprednisolone EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methylprednisolone EP Impurity F be shipped internationally?

Yes. We export Methylprednisolone EP Impurity F worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.