VNL2(DiHydrochloride)

Name: VNL2(DiHydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-013856

About VNL2(DiHydrochloride)

VNL2(DiHydrochloride) is a process intermediate or related compound of Venetoclax carrying the CAS registry number 1628047-87-9. Formula C19H29Cl3N2, molecular weight 391.8 g/mol. Systematically, it is named 1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazine. Dihydrochloride. Common synonyms include CS-B1506 and 1-[[2-(4-chlorophenyl)-4,4-di.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Venetoclax, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies VNL2(DiHydrochloride) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Venetoclax

View every impurity, metabolite and intermediate we list for Venetoclax.

Venetoclax impurities

Specifications & identifiers

Chemical identifiers
Product name	VNL2(DiHydrochloride)
Catalogue No.	VQ-013856
CAS Number	1628047-87-9
Other CAS	1228780-72-0
IUPAC name	1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazine;dihydrochloride
Molecular formula	C₁₉H₂₉Cl₃N₂
Molecular weight	391.8 g/mol
Exact mass	390.1396
Grade	Reference Standard
HSN code	2933
InChIKey	KISZDCHFJKYNFW-UHFFFAOYSA-N
SMILES	CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCNCC3)C.Cl.Cl
PubChem CID	90404543

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 2
TPSA	15.3 Å²
Synonyms	1-((2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride, 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride, 1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine 2HCl salt, 1-((2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazine dihydrochloride, CS-B1506, 1-[[2-(4-chlorophenyl)-4,4-di, 1-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]piperazine dihydrochloride, 1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine diHCl

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of VNL2(DiHydrochloride)?

The CAS Registry Number of VNL2(DiHydrochloride) is 1628047-87-9. It is also known as 1-((2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride, 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride, 1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine 2HCl salt.

What is the molecular formula and molecular weight of VNL2(DiHydrochloride)?

VNL2(DiHydrochloride) has the molecular formula C19H29Cl3N2 and a molecular weight of 391.8 g/mol.

What is VNL2(DiHydrochloride) used for?

VNL2(DiHydrochloride) is supplied as a characterised reference material related to Venetoclax. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of VNL2(DiHydrochloride) can I order?

We supply VNL2(DiHydrochloride) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with VNL2(DiHydrochloride)?

Yes. Every lot of VNL2(DiHydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can VNL2(DiHydrochloride) be shipped internationally?

Yes. VNL2(DiHydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.