Trimethoprim EP Impurity F

Name: Trimethoprim EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-023939

About Trimethoprim EP Impurity F

Trimethoprim EP Impurity F (CAS 16285-82-8) is a pharmacopeial impurity of Trimethoprim offered by Vaqora Chemicals. The compound has the formula C13H15BrN4O2, corresponding to a molecular weight of 339.19 g/mol. Systematically, it is named 5-[(3-bromo-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine. Alternative names: Trimethoprim - Impurity F and Trimethoprim impurity F.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Trimethoprim to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Trimethoprim EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim EP Impurity F
Catalogue No.	VQ-023939
CAS Number	16285-82-8
IUPAC name	5-[(3-bromo-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Molecular formula	C₁₃H₁₅BrN₄O₂
Molecular weight	339.19 g/mol
Exact mass	338.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	XJSNBPJINGRLAM-UHFFFAOYSA-N
SMILES	COC1=C(C(=CC(=C1)CC2=CN=C(N=C2N)N)Br)OC
PubChem CID	3008014

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 6
TPSA	96.3 Å²
Synonyms	Trimethoprim - Impurity F, 2,4-Diamino-5-(3-bromo-4,5-dimethoxybenzyl)pyrimidine, Trimethoprim impurity F, 3-Desmethoxy-3-bromo Trimethoprim, 5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine, 4-Desmethoxy-4-bromo Trimethoprim, 2,4-Pyrimidinediamine, 5-((3-bromo-4,5-dimethoxyphenyl)methyl)-, 5-((3-bromo-4,5-dimethoxyphenyl)methyl)-2,4-pyrimidinediamine, 5-[(3-bromo-4,5-dimethoxy-phenyl)methyl]pyrimidine-2,4-diamine, 2,4-Pyrimidinediamine, 5-[(3-bromo-4,5-dimethoxyphenyl)methyl]-, 5-(3-bromo-4,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim EP Impurity F?

The CAS Registry Number of Trimethoprim EP Impurity F is 16285-82-8. It is also known as Trimethoprim - Impurity F, 2,4-Diamino-5-(3-bromo-4,5-dimethoxybenzyl)pyrimidine, Trimethoprim impurity F.

What is the molecular formula and molecular weight of Trimethoprim EP Impurity F?

Trimethoprim EP Impurity F has the molecular formula C13H15BrN4O2 and a molecular weight of 339.19 g/mol. Its IUPAC name is 5-[(3-bromo-4,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine.

What is Trimethoprim EP Impurity F used for?

Trimethoprim EP Impurity F is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim EP Impurity F can I order?

We supply Trimethoprim EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim EP Impurity F?

Yes. Every lot of Trimethoprim EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim EP Impurity F be shipped internationally?

Yes. Trimethoprim EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.