Terfenadine EP Impurity B

Name: Terfenadine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-043858

About Terfenadine EP Impurity B

Terfenadine EP Impurity B (CAS 1632048-95-3) is a pharmacopeial impurity of Terfenadine offered by Vaqora Chemicals. Its molecular formula is C32H41NO and its molecular weight is 455.7 g/mol. Systematically, it is named 4-(4-benzhydrylpiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-ol. Alternative names: Terfenadine - Impurity B and Terfenadine EP Impurity B (Free Base).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Terfenadine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Terfenadine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Terfenadine

View every impurity, metabolite and intermediate we list for Terfenadine.

Terfenadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Terfenadine EP Impurity B
Catalogue No.	VQ-043858
CAS Number	1632048-95-3
IUPAC name	4-(4-benzhydrylpiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-ol
Molecular formula	C₃₂H₄₁NO
Molecular weight	455.7 g/mol
Exact mass	455.3188
Grade	Reference Standard
HSN code	38229090
InChIKey	JKSNSYGKAXLLAM-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)O
PubChem CID	59872275

Physical properties
Physical form	Solid
LogP (XLogP3)	7.6
H-bond donors / acceptors	1 / 2
TPSA	23.5 Å²
Synonyms	Terfenadine - Impurity B, Terfenadine EP Impurity B (Free Base), (1RS)-1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethyl)piperidin-1-yl)butan-1-ol, 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(diphenylmethyl)-, alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(diphenylmethyl)-1-piperidinebutanol, (1RS)-1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethyl)piperidin-1-yl]butan-1-ol, Terfenadine impurity B, Dehydroxy Terfenadine, DehydroxyTerfenadine, (1RS)-1-[4-(1,1-Dimethylethyl)-phenyl]-4-[4-(diphenylmethyl)piperidin-1-yl]butan-1-ol, 4-(4-Benzhydrylpiperidin-1-yl)-1-(4-(tert-butyl)phenyl)butan-1-ol, (1RS)-1-[4-(1,1-dimethylethyl)- phenyl]-4-[4-(diphenylmethyl)piperidin-1-yl]butan-1-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Terfenadine EP Impurity B?

The CAS Registry Number of Terfenadine EP Impurity B is 1632048-95-3. It is also known as Terfenadine - Impurity B, Terfenadine EP Impurity B (Free Base), (1RS)-1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethyl)piperidin-1-yl)butan-1-ol.

What is the molecular formula and molecular weight of Terfenadine EP Impurity B?

Terfenadine EP Impurity B has the molecular formula C32H41NO and a molecular weight of 455.7 g/mol. Its IUPAC name is 4-(4-benzhydrylpiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-ol.

What is Terfenadine EP Impurity B used for?

Terfenadine EP Impurity B is supplied as a characterised reference material related to Terfenadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Terfenadine EP Impurity B can I order?

We supply Terfenadine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Terfenadine EP Impurity B?

Yes. Every lot of Terfenadine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Terfenadine EP Impurity B be shipped internationally?

Yes. Terfenadine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.