Axitinib Impurity H

Name: Axitinib Impurity H
Brand: Vaqora Chemicals
SKU: VQ-024460

About Axitinib Impurity H

Listed under CAS 1639137-80-6, Axitinib Impurity H is an impurity of Axitinib available from Vaqora Chemicals. The compound has the formula C24H20N4O2S, corresponding to a molecular weight of 428.5 g/mol. Systematically, it is named 2-[1-acetyl-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanyl-N-methylbenzamide. It is also known as Axitinib N-Acetyl impurity or N-Acetyl Axitinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Axitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Axitinib Impurity H is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Axitinib Impurity H
Catalogue No.	VQ-024460
CAS Number	1639137-80-6
IUPAC name	2-[1-acetyl-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanyl-N-methylbenzamide
Molecular formula	C₂₄H₂₀N₄O₂S
Molecular weight	428.5 g/mol
Exact mass	428.1307
Grade	Reference Standard
HSN code	38229090
InChIKey	DPCLTPPDTUVUIL-JLHYYAGUSA-N
SMILES	CC(=O)N1C2=C(C=CC(=C2)SC3=CC=CC=C3C(=O)NC)C(=N1)/C=C/C4=CC=CC=N4
PubChem CID	156118407

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 5
TPSA	102 Å²
Synonyms	Axitinib N-Acetyl impurity, N-Acetyl Axitinib, Axitinib Impurity N, 2-[[1-Acetyl-3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-N-methylbenzamide, 2-[1-acetyl-3-[(E)-2-(2-pyridyl)vinyl]indazol-6-yl]sulfanyl-N-methyl-benzamide, Benzamide, 2-[[1-acetyl-3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-N-methyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Axitinib Impurity H?

The CAS Registry Number of Axitinib Impurity H is 1639137-80-6. It is also known as Axitinib N-Acetyl impurity, N-Acetyl Axitinib, Axitinib Impurity N.

What is the molecular formula and molecular weight of Axitinib Impurity H?

Axitinib Impurity H has the molecular formula C24H20N4O2S and a molecular weight of 428.5 g/mol. Its IUPAC name is 2-[1-acetyl-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanyl-N-methylbenzamide.

What is Axitinib Impurity H used for?

Axitinib Impurity H is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Axitinib Impurity H can I order?

We supply Axitinib Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Axitinib Impurity H?

Yes. Every lot of Axitinib Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Axitinib Impurity H be shipped internationally?

Yes. We export Axitinib Impurity H worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.