(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2… 1643811-26-0

About (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid is a metabolite or degradation product of Avanafil carrying the CAS registry number 1643811-26-0. Formula C18H20Cl2N4O4, molecular weight 427.3 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Avanafil, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Avanafil

View every impurity, metabolite and intermediate we list for Avanafil.

Avanafil impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
Catalogue No.	VQ-043987
CAS Number	1643811-26-0
IUPAC name	4-[(3,5-dichloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid
Molecular formula	C₁₈H₂₀Cl₂N₄O₄
Molecular weight	427.3 g/mol
Exact mass	426.0862
Grade	Reference Standard
HSN code	38229090
InChIKey	GXYDPSROSVJWPO-NSHDSACASA-N
SMILES	COC1=C(C=C(C=C1Cl)CNC2=NC(=NC=C2C(=O)O)N3CCC[C@H]3CO)Cl
PubChem CID	154631349

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 8
TPSA	108 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid?

The CAS Registry Number of (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid is 1643811-26-0.

What is the molecular formula and molecular weight of (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid?

(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid has the molecular formula C18H20Cl2N4O4 and a molecular weight of 427.3 g/mol. Its IUPAC name is 4-[(3,5-dichloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid.

What is (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid used for?

(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid is supplied as a characterised reference material related to Avanafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid can I order?

We supply (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid?

Yes. Every lot of (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid be shipped internationally?

Yes. We export (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.