Pemetrexed Alpha-hydroxy lactum

About Pemetrexed Alpha-hydroxy lactum

Pemetrexed Alpha-hydroxy lactum is a metabolite or degradation product of Pemetrexed carrying the CAS registry number 1644286-36-1. Formula C20H21N5O8, molecular weight 459.4 g/mol. It is also known as Pemetrexed Hydroxy lactam or Deoxo Pemetrexed.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Pemetrexed, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Pemetrexed Alpha-hydroxy lactum is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Alpha-hydroxy lactum
Catalogue No.	VQ-033089
CAS Number	1644286-36-1
IUPAC name	(2S)-2-[[4-[2-(2-amino-5-hydroxy-4,6-dioxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₁N₅O₈
Molecular weight	459.4 g/mol
Exact mass	459.139
Grade	Reference Standard
HSN code	38229090
InChIKey	GAKTVWRVKYXKTO-ZOZMEPSFSA-N
SMILES	C1=CC(=CC=C1CCC2(C3=C(NC2=O)N=C(NC3=O)N)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	145709242

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.9
H-bond donors / acceptors	7 / 9
TPSA	221 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Alpha-hydroxy lactum?

The CAS Registry Number of Pemetrexed Alpha-hydroxy lactum is 1644286-36-1. It is also known as Pemetrexed Hydroxy lactam, Deoxo Pemetrexed, Deoxo Pemetrexed (DISCONTINUED).

What is the molecular formula and molecular weight of Pemetrexed Alpha-hydroxy lactum?

Pemetrexed Alpha-hydroxy lactum has the molecular formula C20H21N5O8 and a molecular weight of 459.4 g/mol. Its IUPAC name is (2S)-2-[[4-[2-(2-amino-5-hydroxy-4,6-dioxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid.

What is Pemetrexed Alpha-hydroxy lactum used for?

Pemetrexed Alpha-hydroxy lactum is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Alpha-hydroxy lactum can I order?

We supply Pemetrexed Alpha-hydroxy lactum in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Alpha-hydroxy lactum?

Yes. Every lot of Pemetrexed Alpha-hydroxy lactum is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Alpha-hydroxy lactum be shipped internationally?

Yes. We export Pemetrexed Alpha-hydroxy lactum worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.