2-(Ethoxycarbonyl)-6-nitrobenzoic acid

Name: 2-(Ethoxycarbonyl)-6-nitrobenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-035781

About 2-(Ethoxycarbonyl)-6-nitrobenzoic acid

Vaqora Chemicals supplies 2-(Ethoxycarbonyl)-6-nitrobenzoic acid, an impurity of Apremilast registered under CAS number 16533-45-2. Formula C10H9NO6, molecular weight 239.18 g/mol. Common synonyms include 1-Ethyl-3-nitrophthalate and Ethyl 2-carboxy-3-nitrobenzoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Apremilast to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Ethoxycarbonyl)-6-nitrobenzoic acid
Catalogue No.	VQ-035781
CAS Number	16533-45-2
IUPAC name	2-ethoxycarbonyl-6-nitrobenzoic acid
Molecular formula	C₁₀H₉NO₆
Molecular weight	239.18 g/mol
Exact mass	239.043
Grade	Reference Standard
HSN code	38229090
InChIKey	SZAOZGFHEAVFMM-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])C(=O)O
PubChem CID	12018928

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 6
TPSA	109 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Ethoxycarbonyl)-6-nitrobenzoic acid?

The CAS Registry Number of 2-(Ethoxycarbonyl)-6-nitrobenzoic acid is 16533-45-2. It is also known as 1-Ethyl-3-nitrophthalate, 1,2-Benzenedicarboxylic acid, 3-nitro-, 1-ethyl ester, Ethyl 2-carboxy-3-nitrobenzoate.

What is the molecular formula and molecular weight of 2-(Ethoxycarbonyl)-6-nitrobenzoic acid?

2-(Ethoxycarbonyl)-6-nitrobenzoic acid has the molecular formula C10H9NO6 and a molecular weight of 239.18 g/mol. Its IUPAC name is 2-ethoxycarbonyl-6-nitrobenzoic acid.

What is 2-(Ethoxycarbonyl)-6-nitrobenzoic acid used for?

2-(Ethoxycarbonyl)-6-nitrobenzoic acid is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Ethoxycarbonyl)-6-nitrobenzoic acid can I order?

We supply 2-(Ethoxycarbonyl)-6-nitrobenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Ethoxycarbonyl)-6-nitrobenzoic acid?

Yes. Every lot of 2-(Ethoxycarbonyl)-6-nitrobenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Ethoxycarbonyl)-6-nitrobenzoic acid be shipped internationally?

Yes. We export 2-(Ethoxycarbonyl)-6-nitrobenzoic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.