Naltrexone

Name: Naltrexone
Brand: Vaqora Chemicals
SKU: VQ-007599

About Naltrexone

Listed under CAS 16590-41-3, Naltrexone is a high-purity reference standard of Naltrexone available from Vaqora Chemicals. The compound has the formula C20H23NO4, corresponding to a molecular weight of 341.4 g/mol. It is also known as (-)-Naltrexone or Depotrex.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Naltrexone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	Naltrexone
Catalogue No.	VQ-007599
CAS Number	16590-41-3
Other CAS	16676-29-2, 850808-02-5
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₂₀H₂₃NO₄
Molecular weight	341.4 g/mol
Exact mass	341.1627
Grade	Reference Standard
HSN code	38229090
InChIKey	DQCKKXVULJGBQN-XFWGSAIBSA-N
SMILES	C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O
PubChem CID	5360515

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 5
TPSA	70 Å²
Synonyms	17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, (-)-Naltrexone, 1-N-Cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone, Depotrex, N-Cyclopropylmethylnoroxymorphone, Naltrel, Nemexin, Trexonil, UM 792, Vivitrex, Vivitrol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H341Suspected of causing genetic defects
H400Very toxic to aquatic life

Precautionary statements: P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P333 + P317, P342 + P316, P362 + P364, P391, P403, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naltrexone?

The CAS Registry Number of Naltrexone is 16590-41-3. It is also known as 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, (-)-Naltrexone.

What is the molecular formula and molecular weight of Naltrexone?

Naltrexone has the molecular formula C20H23NO4 and a molecular weight of 341.4 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is Naltrexone used for?

Naltrexone is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naltrexone can I order?

We supply Naltrexone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naltrexone?

Yes. Every lot of Naltrexone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naltrexone be shipped internationally?

Yes. Naltrexone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.