Bromohexine EP Impurity E Chloride

About Bromohexine EP Impurity E Chloride

Bromohexine EP Impurity E Chloride is a pharmacopeial impurity of Bromhexine carrying the CAS registry number 1660957-93-6. With the molecular formula C15H21Br2ClN2, it has a molar mass of 424.6 g/mol. Its systematic (IUPAC) name is 6,8-dibromo-3-cyclohexyl-3-methyl-2,4-dihydro-1H-quinazolin-3-ium chloride. Common synonyms include Bromhexine EP Impurity E (Chloride Salt) and Bromhexine EP Impurity E (Chloride).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Bromhexine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Bromohexine EP Impurity E Chloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Bromhexine

View every impurity, metabolite and intermediate we list for Bromhexine.

Bromhexine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Bromohexine EP Impurity E Chloride
Catalogue No.	VQ-024667
CAS Number	1660957-93-6
IUPAC name	6,8-dibromo-3-cyclohexyl-3-methyl-2,4-dihydro-1H-quinazolin-3-ium chloride
Molecular formula	C₁₅H₂₁Br₂ClN₂
Molecular weight	424.6 g/mol
Exact mass	423.974
Grade	Reference Standard
HSN code	38229090
InChIKey	VAJTZQWUDKDOPK-UHFFFAOYSA-M
SMILES	C[N+]1(CC2=C(C(=CC(=C2)Br)Br)NC1)C3CCCCC3.[Cl-]
PubChem CID	122360610

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	12 Å²
Synonyms	Bromhexine EP Impurity E (Chloride Salt), Bromhexine EP Impurity E (Chloride), Bromhexine Hydrochloride - Impurity E (Chloride Salt), Bromhexine Impurity E chloride, 3-Cyclohexyl-6,8-dibrom-3-methyl-1,2,3,4-tetrahydro-chinazoliumchlorid, 3-Cyclohexyl-6,8-dibromo-3-methyl-1,2,3,4-tetrahydroquinazolinium Chloride, 6,8-Dibromo-3-cyclohexyl-3-methyl-1,2,3,4-tetrahydroquinazolin-3-ium chloride, (3RS)-6,8-Dibromo-3-cyclohexyl-3-methyl-1,2,3,4-tetrahydroquinazolin-3-ium Chloride, 6,8-Dibromo-3-cyclohexyl-3-methyl-1,2,3,4-tetrahydroquinazolin-3-iumchloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bromohexine EP Impurity E Chloride?

The CAS Registry Number of Bromohexine EP Impurity E Chloride is 1660957-93-6. It is also known as Bromhexine EP Impurity E (Chloride Salt), Bromhexine EP Impurity E (Chloride), Bromhexine Hydrochloride - Impurity E (Chloride Salt).

What is the molecular formula and molecular weight of Bromohexine EP Impurity E Chloride?

Bromohexine EP Impurity E Chloride has the molecular formula C15H21Br2ClN2 and a molecular weight of 424.6 g/mol. Its IUPAC name is 6,8-dibromo-3-cyclohexyl-3-methyl-2,4-dihydro-1H-quinazolin-3-ium chloride.

What is Bromohexine EP Impurity E Chloride used for?

Bromohexine EP Impurity E Chloride is supplied as a characterised reference material related to Bromhexine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bromohexine EP Impurity E Chloride can I order?

We supply Bromohexine EP Impurity E Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bromohexine EP Impurity E Chloride?

Yes. Every lot of Bromohexine EP Impurity E Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bromohexine EP Impurity E Chloride be shipped internationally?

Yes. Bromohexine EP Impurity E Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.