Naltrexone Hydrochloride

Name: Naltrexone Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007600

About Naltrexone Hydrochloride

Listed under CAS 16676-29-2, Naltrexone Hydrochloride is a high-purity reference standard of Naltrexone available from Vaqora Chemicals. With the molecular formula C20H24ClNO4, it has a molar mass of 377.9 g/mol. It is also known as Antaxone Hydrochloride or Depade Hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Naltrexone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Naltrexone Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	Naltrexone Hydrochloride
Catalogue No.	VQ-007600
CAS Number	16676-29-2
Other CAS	16590-41-3, 850808-02-5
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
Molecular formula	C₂₀H₂₄ClNO₄
Molecular weight	377.9 g/mol
Exact mass	377.1394
Grade	Reference Standard
HSN code	38229090
InChIKey	RHBRMCOKKKZVRY-ITLPAZOVSA-N
SMILES	C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl
PubChem CID	5485201

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 5
TPSA	70 Å²
Synonyms	17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy morphinan-6-one hydrochloride, (5α)-17-(Cyclopropyl-methyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride, Antaxone Hydrochloride, Depade Hydrochloride, Nalorex Hydrochloride, Trexan Hydrochloride, Naltrexone Hcl, En 1639A, EN-1639A, N-Cyclopropylmethyl-noroxymorphone hydrochloride, (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, 17-(Cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-one hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H341Suspected of causing genetic defects

Precautionary statements: P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naltrexone Hydrochloride?

The CAS Registry Number of Naltrexone Hydrochloride is 16676-29-2. It is also known as 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy morphinan-6-one hydrochloride, (5α)-17-(Cyclopropyl-methyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride, Antaxone Hydrochloride.

What is the molecular formula and molecular weight of Naltrexone Hydrochloride?

Naltrexone Hydrochloride has the molecular formula C20H24ClNO4 and a molecular weight of 377.9 g/mol.

What is Naltrexone Hydrochloride used for?

Naltrexone Hydrochloride is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naltrexone Hydrochloride can I order?

We supply Naltrexone Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naltrexone Hydrochloride?

Yes. Every lot of Naltrexone Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naltrexone Hydrochloride be shipped internationally?

Yes. Naltrexone Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.