Darunavir Diamino (2R,3S) Isomer

Name: Darunavir Diamino (2R,3S) Isomer
Brand: Vaqora Chemicals
SKU: VQ-004736

About Darunavir Diamino (2R,3S) Isomer

Darunavir Diamino (2R,3S) Isomer (CAS 169280-56-2) is an impurity of Darunavir offered by Vaqora Chemicals. The compound has the formula C20H29N3O3S, corresponding to a molecular weight of 391.5 g/mol. Its systematic (IUPAC) name is 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide. Alternative names: Darunavir Intermediate 22 and BOC-8.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This Darunavir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Darunavir Diamino (2R,3S) Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	Darunavir Diamino (2R,3S) Isomer
Catalogue No.	VQ-004736
CAS Number	169280-56-2
IUPAC name	4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide
Molecular formula	C₂₀H₂₉N₃O₃S
Molecular weight	391.5 g/mol
Exact mass	391.193
Grade	Reference Standard
HSN code	38229090
InChIKey	NUMJNKDUHFCFJO-VQTJNVASSA-N
SMILES	CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)N)O)S(=O)(=O)C2=CC=C(C=C2)N
PubChem CID	9888792

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 6
TPSA	118 Å²
Synonyms	4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide, Darunavir Diamino (2R,3S) Isomer, N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)-4-aminobenzenesulfonamide, (2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-amino-benzenesulfonamide, 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)benzenesulfonamide, 4-amino-n-((2r,3s)-3-amino-2-hydroxy-4-phenylbutyl)-n-isobutylbenzene-1-sulfonamide, 4-amino-N-(2R,3S)(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide, 4-amino-n-[(2r,3s)-3-amino-2-hydroxy-4-phenylbutyl]-n-isobutylbenzenesulfonamide, Darunavir Intermediate 22, BOC-8, Darunavir metabolite 19, R374699, 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenyl-butyl]-N-isobutyl-benzenesulfonamide

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H318Causes serious eye damage
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264 + P265, P272, P273, P280, P302 + P352, P305 + P354 + P338, P317, P319, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Darunavir Diamino (2R,3S) Isomer?

The CAS Registry Number of Darunavir Diamino (2R,3S) Isomer is 169280-56-2. It is also known as 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide, Darunavir Diamino (2R,3S) Isomer, N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)-4-aminobenzenesulfonamide.

What is the molecular formula and molecular weight of Darunavir Diamino (2R,3S) Isomer?

Darunavir Diamino (2R,3S) Isomer has the molecular formula C20H29N3O3S and a molecular weight of 391.5 g/mol. Its IUPAC name is 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide.

What is Darunavir Diamino (2R,3S) Isomer used for?

Darunavir Diamino (2R,3S) Isomer is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Darunavir Diamino (2R,3S) Isomer can I order?

We supply Darunavir Diamino (2R,3S) Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Darunavir Diamino (2R,3S) Isomer?

Yes. Every lot of Darunavir Diamino (2R,3S) Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Darunavir Diamino (2R,3S) Isomer be shipped internationally?

Yes. Darunavir Diamino (2R,3S) Isomer is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.