Ketoconazole Hydroxymethyl Impurity

About Ketoconazole Hydroxymethyl Impurity

Ketoconazole Hydroxymethyl Impurity is an impurity of Ketoconazole carrying the CAS registry number 170210-42-1. Its molecular formula is C14H14Cl2N2O3 and its molecular weight is 329.2 g/mol. Its systematic (IUPAC) name is [(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol. Common synonyms include Ketoconazole Impurity 16 and Ketoconazole Impurity N15.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Ketoconazole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ketoconazole Hydroxymethyl Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole Hydroxymethyl Impurity
Catalogue No.	VQ-031370
CAS Number	170210-42-1
IUPAC name	[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
Molecular formula	C₁₄H₁₄Cl₂N₂O₃
Molecular weight	329.2 g/mol
Exact mass	328.0381
Grade	Reference Standard
HSN code	38229090
InChIKey	VJZJGRMLFMJRGG-FZMZJTMJSA-N
SMILES	C1[C@@H](O[C@@](O1)(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)CO
PubChem CID	794639

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 4
TPSA	56.5 Å²
Synonyms	rel-(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, Ketoconazole Impurity 16, cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, ((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol, Ketoconazole Impurity N15, Ketoconazole Impurity 13 (and enantiomer), [2-(2,4-Dichloro-phenyl)-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-yl]-methanol, {(2R,4S)-2-(2,4-Dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl}methanol, 2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, (2R,4S)-(+/-)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketoconazole Hydroxymethyl Impurity?

The CAS Registry Number of Ketoconazole Hydroxymethyl Impurity is 170210-42-1. It is also known as rel-(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol, Ketoconazole Impurity 16, cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol.

What is the molecular formula and molecular weight of Ketoconazole Hydroxymethyl Impurity?

Ketoconazole Hydroxymethyl Impurity has the molecular formula C14H14Cl2N2O3 and a molecular weight of 329.2 g/mol. Its IUPAC name is [(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol.

What is Ketoconazole Hydroxymethyl Impurity used for?

Ketoconazole Hydroxymethyl Impurity is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole Hydroxymethyl Impurity can I order?

We supply Ketoconazole Hydroxymethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole Hydroxymethyl Impurity?

Yes. Every lot of Ketoconazole Hydroxymethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole Hydroxymethyl Impurity be shipped internationally?

Yes. We export Ketoconazole Hydroxymethyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.