Fosaprepitant

About Fosaprepitant

Fosaprepitant is a high-purity reference standard of Fosaprepitant carrying the CAS registry number 172673-20-0. The compound has the formula C23H22F7N4O6P, corresponding to a molecular weight of 614.4 g/mol. Alternative names: Ivemend and Fosaprepitant (INN).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Fosaprepitant, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Fosaprepitant

View every impurity, metabolite and intermediate we list for Fosaprepitant.

Fosaprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Fosaprepitant
Catalogue No.	VQ-007489
CAS Number	172673-20-0
IUPAC name	[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid
Molecular formula	C₂₃H₂₂F₇N₄O₆P
Molecular weight	614.4 g/mol
Exact mass	614.1165
Grade	Reference Standard
HSN code	38229090
InChIKey	BARDROPHSZEBKC-OITMNORJSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C(C=C4)F
PubChem CID	135413538

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	3 / 15
TPSA	124 Å²
Synonyms	Ivemend, Fosaprepitant (INN), emend(R) IV, fosaprepitant-dimeglumine, EX-A1255A

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fosaprepitant?

The CAS Registry Number of Fosaprepitant is 172673-20-0. It is also known as Ivemend, Fosaprepitant (INN), emend(R) IV.

What is the molecular formula and molecular weight of Fosaprepitant?

Fosaprepitant has the molecular formula C23H22F7N4O6P and a molecular weight of 614.4 g/mol. Its IUPAC name is [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid.

What is Fosaprepitant used for?

Fosaprepitant is supplied as a characterised reference material related to Fosaprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fosaprepitant can I order?

We supply Fosaprepitant in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fosaprepitant?

Yes. Every lot of Fosaprepitant is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fosaprepitant be shipped internationally?

Yes. We export Fosaprepitant worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.