1-[4-(Trifluoromethyl)phenyl]-2-thiourea

Name: 1-[4-(Trifluoromethyl)phenyl]-2-thiourea
Brand: Vaqora Chemicals
SKU: VQ-041910

About 1-[4-(Trifluoromethyl)phenyl]-2-thiourea

1-[4-(Trifluoromethyl)phenyl]-2-thiourea (CAS 1736-72-7) is a process intermediate or related compound of Riluzole offered by Vaqora Chemicals. Its molecular formula is C8H7F3N2S and its molecular weight is 220.22 g/mol. Systematically, it is named [4-(trifluoromethyl)phenyl]thiourea. Alternative names: (4-(Trifluoromethyl)phenyl)thiourea and 1-(4-(Trifluoromethyl)phenyl)thiourea.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Riluzole, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-[4-(Trifluoromethyl)phenyl]-2-thiourea is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Riluzole

View every impurity, metabolite and intermediate we list for Riluzole.

Riluzole impurities

Specifications & identifiers

Chemical identifiers
Product name	1-[4-(Trifluoromethyl)phenyl]-2-thiourea
Catalogue No.	VQ-041910
CAS Number	1736-72-7
IUPAC name	[4-(trifluoromethyl)phenyl]thiourea
Molecular formula	C₈H₇F₃N₂S
Molecular weight	220.22 g/mol
Exact mass	220.0282
HSN code	2933
InChIKey	OWTDDZMFRLUBQI-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)(F)F)NC(=S)N
PubChem CID	2777727

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	2 / 4
TPSA	70.1 Å²
Synonyms	(4-(Trifluoromethyl)phenyl)thiourea, 1-(4-(Trifluoromethyl)phenyl)thiourea, 4-(trifluoromethyl)phenylthiourea, n-[4-(trifluoromethyl)phenyl]thiourea, Thiourea, N-[4-(trifluoromethyl)phenyl]-, [4-(Trifluoromethyl)phenyl] Thiourea, amino{[4-(trifluoromethyl)phenyl]amino}methane-1-thione, Thiourea, [4-(trifluoromethyl)phenyl]-, (4-trifluoromethyl-phenyl)-thiourea, a,a,a-trifluoro-p-tolylthiourea, (4-trifluoromethylphenyl)thiourea, 4-(trifluoromethyl)phenyl thiourea

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P272, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-[4-(Trifluoromethyl)phenyl]-2-thiourea?

The CAS Registry Number of 1-[4-(Trifluoromethyl)phenyl]-2-thiourea is 1736-72-7. It is also known as (4-(Trifluoromethyl)phenyl)thiourea, 1-(4-(Trifluoromethyl)phenyl)thiourea, 4-(trifluoromethyl)phenylthiourea.

What is the molecular formula and molecular weight of 1-[4-(Trifluoromethyl)phenyl]-2-thiourea?

1-[4-(Trifluoromethyl)phenyl]-2-thiourea has the molecular formula C8H7F3N2S and a molecular weight of 220.22 g/mol. Its IUPAC name is [4-(trifluoromethyl)phenyl]thiourea.

What is 1-[4-(Trifluoromethyl)phenyl]-2-thiourea used for?

1-[4-(Trifluoromethyl)phenyl]-2-thiourea is supplied as a characterised reference material related to Riluzole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-[4-(Trifluoromethyl)phenyl]-2-thiourea can I order?

We supply 1-[4-(Trifluoromethyl)phenyl]-2-thiourea, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-[4-(Trifluoromethyl)phenyl]-2-thiourea?

Yes. Every lot of 1-[4-(Trifluoromethyl)phenyl]-2-thiourea is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-[4-(Trifluoromethyl)phenyl]-2-thiourea be shipped internationally?

Yes. 1-[4-(Trifluoromethyl)phenyl]-2-thiourea is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.