2,2-Bisnalmefene

About 2,2-Bisnalmefene

2,2-Bisnalmefene is an impurity of Nalmefene carrying the CAS registry number 176220-84-1. With the molecular formula C42H48N2O6, it has a molar mass of 676.8 g/mol. Common synonyms include 2,2'-Bis(6-deoxo-6-methylenenaltrexone) and 2,2'-bis(6-Deox o-6-methylenenaltrexone).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Nalmefene to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2,2-Bisnalmefene in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nalmefene

View every impurity, metabolite and intermediate we list for Nalmefene.

Nalmefene impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2-Bisnalmefene
Catalogue No.	VQ-026820
CAS Number	176220-84-1
IUPAC name	(4R,4aS,7aS,12bS)-10-[(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-10-yl]-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Molecular formula	C₄₂H₄₈N₂O₆
Molecular weight	676.8 g/mol
Exact mass	676.3512
Grade	Reference Standard
HSN code	38229090
InChIKey	DEKUTJDLMXTWRE-CVQRZJKKSA-N
SMILES	C=C1CC[C@]2([C@H]3CC4=CC(=C(C5=C4[C@]2([C@H]1O5)CCN3CC6CC6)O)C7=C(C8=C9C(=C7)C[C@@H]1[C@]2([C@]9(CCN1CC1CC1)[C@@H](O8)C(=C)CC2)O)O)O
PubChem CID	5491397

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	4 / 8
TPSA	106 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2-Bisnalmefene?

The CAS Registry Number of 2,2-Bisnalmefene is 176220-84-1. It is also known as 2,2'-Bis(6-deoxo-6-methylenenaltrexone), 2,2'-bis(6-Deox o-6-methylenenaltrexone).

What is the molecular formula and molecular weight of 2,2-Bisnalmefene?

2,2-Bisnalmefene has the molecular formula C42H48N2O6 and a molecular weight of 676.8 g/mol.

What is 2,2-Bisnalmefene used for?

2,2-Bisnalmefene is supplied as a characterised reference material related to Nalmefene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2-Bisnalmefene can I order?

We supply 2,2-Bisnalmefene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2-Bisnalmefene?

Yes. Every lot of 2,2-Bisnalmefene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2-Bisnalmefene be shipped internationally?

Yes. We export 2,2-Bisnalmefene worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.