2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Aci… 178306-47-3

About 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester is a metabolite or degradation product of Ambrisentan carrying the CAS registry number 178306-47-3. Its molecular formula is C17H18O4 and its molecular weight is 286.32 g/mol. Systematically, it is named methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate. It is also known as ALST-01 or PI-4.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Ambrisentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester
Catalogue No.	VQ-049530
CAS Number	178306-47-3
IUPAC name	methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
Molecular formula	C₁₇H₁₈O₄
Molecular weight	286.32 g/mol
Exact mass	286.1205
Grade	Reference Standard
HSN code	38229090
InChIKey	BEPLSLADXOJCBY-UHFFFAOYSA-N
SMILES	COC(=O)C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OC)O
PubChem CID	10541193

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 4
TPSA	55.8 Å²
Synonyms	Benzenepropanoic acid, alpha-hydroxy-beta-methoxy-beta-phenyl-, methyl ester, Methyl 2-hydroxy-3-methoxy-3,3-diphenyl-propanoate, ALST-01, PI-4, 2-hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester, 3-diphenylpropanoic acid methyl ester, benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,methyl ester, Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropionate, methyl-2-hydroxy-3-methoxy-3,3-diphenylpropionate, methyl2-hydroxy-3-methoxy-3,3-diphenylpropanoate, methyl 2-hydroxy-3-methoxy-3,3-diphenyl-propionate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester?

The CAS Registry Number of 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester is 178306-47-3. It is also known as Benzenepropanoic acid, alpha-hydroxy-beta-methoxy-beta-phenyl-, methyl ester, Methyl 2-hydroxy-3-methoxy-3,3-diphenyl-propanoate, ALST-01.

What is the molecular formula and molecular weight of 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester?

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester has the molecular formula C17H18O4 and a molecular weight of 286.32 g/mol. Its IUPAC name is methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate.

What is 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester used for?

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester can I order?

We supply 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester?

Yes. Every lot of 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester be shipped internationally?

Yes. We export 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.