N-(R)-Glycidyl Phthalimide

Name: N-(R)-Glycidyl Phthalimide
Brand: Vaqora Chemicals
SKU: VQ-027148

About N-(R)-Glycidyl Phthalimide

Listed under CAS 181140-34-1, N-(R)-Glycidyl Phthalimide is an impurity of Rivaroxaban available from Vaqora Chemicals. Formula C11H9NO3, molecular weight 203.19 g/mol. Its systematic (IUPAC) name is 2-[[(2R)-oxiran-2-yl]methyl]isoindole-1,3-dione. It is also known as (R)-(-)-N-(2,3-Epoxypropyl)phthalimide or (R)-N-Glycidylphthalimide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Rivaroxaban impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-(R)-Glycidyl Phthalimide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(R)-Glycidyl Phthalimide
Catalogue No.	VQ-027148
CAS Number	181140-34-1
IUPAC name	2-[[(2R)-oxiran-2-yl]methyl]isoindole-1,3-dione
Molecular formula	C₁₁H₉NO₃
Molecular weight	203.19 g/mol
Exact mass	203.0582
Grade	Reference Standard
HSN code	38229090
InChIKey	DUILGEYLVHGSEE-SSDOTTSWSA-N
SMILES	C1[C@H](O1)CN2C(=O)C3=CC=CC=C3C2=O
PubChem CID	719415

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	0 / 3
TPSA	49.9 Å²
Synonyms	(R)-(-)-N-(2,3-Epoxypropyl)phthalimide, 2-{[(2R)-oxiran-2-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione, 2-(((2R)-oxiran-2-yl)methyl)-2,3-dihydro-1H-isoindole-1,3-dione, (R)-N-Glycidylphthalimide, (R)-2-(oxiran-2-ylmethyl)isoindoline-1,3-dione, 1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-oxiranylmethyl]-, (R)-Glycidyl phthalimide, Glycidyl phthalimide, (R)-, (R)-(-)-Glycidyl phthalimide, 2-[(2R)-2-oxiranylmethyl]-1H-isoindole-1,3(2H)-dione, (R)-N-(2,3-Epoxypropyl)phthalimide

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(R)-Glycidyl Phthalimide?

The CAS Registry Number of N-(R)-Glycidyl Phthalimide is 181140-34-1. It is also known as (R)-(-)-N-(2,3-Epoxypropyl)phthalimide, 2-{[(2R)-oxiran-2-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione, 2-(((2R)-oxiran-2-yl)methyl)-2,3-dihydro-1H-isoindole-1,3-dione.

What is the molecular formula and molecular weight of N-(R)-Glycidyl Phthalimide?

N-(R)-Glycidyl Phthalimide has the molecular formula C11H9NO3 and a molecular weight of 203.19 g/mol. Its IUPAC name is 2-[[(2R)-oxiran-2-yl]methyl]isoindole-1,3-dione.

What is N-(R)-Glycidyl Phthalimide used for?

N-(R)-Glycidyl Phthalimide is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(R)-Glycidyl Phthalimide can I order?

We supply N-(R)-Glycidyl Phthalimide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(R)-Glycidyl Phthalimide?

Yes. Every lot of N-(R)-Glycidyl Phthalimide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(R)-Glycidyl Phthalimide be shipped internationally?

Yes. N-(R)-Glycidyl Phthalimide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.