Cabozantinib Hydrochloride

Name: Cabozantinib Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-044244

About Cabozantinib Hydrochloride

Cabozantinib Hydrochloride is a high-purity reference standard of Cabozantinib carrying the CAS registry number 1817759-42-4. Formula C28H25ClFN3O5, molecular weight 538.0 g/mol. It is also known as Cabozantinib hydrochloride (1:1).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Cabozantinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cabozantinib Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabozantinib Hydrochloride
Catalogue No.	VQ-044244
CAS Number	1817759-42-4
IUPAC name	1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;hydrochloride
Molecular formula	C₂₈H₂₅ClFN₃O₅
Molecular weight	538 g/mol
Exact mass	537.1467
Grade	Reference Standard
HSN code	38229090
InChIKey	LCNVAOXPKXBXEH-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.Cl
PubChem CID	122573030

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 7
TPSA	98.8 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabozantinib Hydrochloride?

The CAS Registry Number of Cabozantinib Hydrochloride is 1817759-42-4. It is also known as Cabozantinib hydrochloride (1:1).

What is the molecular formula and molecular weight of Cabozantinib Hydrochloride?

Cabozantinib Hydrochloride has the molecular formula C28H25ClFN3O5 and a molecular weight of 538 g/mol.

What is Cabozantinib Hydrochloride used for?

Cabozantinib Hydrochloride is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabozantinib Hydrochloride can I order?

We supply Cabozantinib Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabozantinib Hydrochloride?

Yes. Every lot of Cabozantinib Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabozantinib Hydrochloride be shipped internationally?

Yes. Cabozantinib Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.