2-Keto-D-Glucose

About 2-Keto-D-Glucose

2-Keto-D-Glucose is an impurity of Tretinoin carrying the CAS registry number 1854-25-7. Its molecular formula is C6H10O6 and its molecular weight is 178.14 g/mol. Its systematic (IUPAC) name is (3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexanal. Alternative names: D-glucosone and D-Arabino-hexos-2-ulose.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Tretinoin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Keto-D-Glucose is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tretinoin

View every impurity, metabolite and intermediate we list for Tretinoin.

Tretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Keto-D-Glucose
Catalogue No.	VQ-040303
CAS Number	1854-25-7
IUPAC name	(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexanal
Molecular formula	C₆H₁₀O₆
Molecular weight	178.14 g/mol
Exact mass	178.0477
Grade	Reference Standard
HSN code	38229090
InChIKey	DCNMIDLYWOTSGK-HSUXUTPPSA-N
SMILES	C([C@H]([C@H]([C@@H](C(=O)C=O)O)O)O)O
PubChem CID	159630

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.9
H-bond donors / acceptors	4 / 6
TPSA	115 Å²
Synonyms	D-glucosone, D-Arabino-hexos-2-ulose, 2-Ketoglucose, GlyTouCan:G50353CY, Glucosone, arabino-Hexos-2-ulose, D-Arabino-2-hexosulose, Arabino-hexosulose, aldehydo-2-keto-D-glucose, D-arabino-hexosul, aldehydo-2-dehydro-D-glucose, (3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxo-hexanal

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Keto-D-Glucose?

The CAS Registry Number of 2-Keto-D-Glucose is 1854-25-7. It is also known as D-glucosone, D-Arabino-hexos-2-ulose, 2-Ketoglucose.

What is the molecular formula and molecular weight of 2-Keto-D-Glucose?

2-Keto-D-Glucose has the molecular formula C6H10O6 and a molecular weight of 178.14 g/mol. Its IUPAC name is (3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexanal.

What is 2-Keto-D-Glucose used for?

2-Keto-D-Glucose is supplied as a characterised reference material related to Tretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Keto-D-Glucose can I order?

We supply 2-Keto-D-Glucose in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Keto-D-Glucose?

Yes. Every lot of 2-Keto-D-Glucose is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Keto-D-Glucose be shipped internationally?

Yes. We export 2-Keto-D-Glucose worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.