O-Desmethyl Tramadol Hydrochloride

Name: O-Desmethyl Tramadol Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-044857

About O-Desmethyl Tramadol Hydrochloride

O-Desmethyl Tramadol Hydrochloride (CAS 185453-02-5) is a metabolite or degradation product of Tramadol offered by Vaqora Chemicals. With the molecular formula C15H24ClNO2, it has a molar mass of 285.81 g/mol. Common synonyms include O-demethyltramadol hydrochloride and O-Desmethyl-cis-tramadol.HCl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tramadol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tramadol

View every impurity, metabolite and intermediate we list for Tramadol.

Tramadol impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Tramadol Hydrochloride
Catalogue No.	VQ-044857
CAS Number	185453-02-5
IUPAC name	3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol;hydrochloride
Molecular formula	C₁₅H₂₄ClNO₂
Molecular weight	285.81 g/mol
Exact mass	285.1496
Grade	Reference Standard
HSN code	38229090
InChIKey	IRGWVAWLHXDKIX-PBCQUBLHSA-N
SMILES	CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)O)O.Cl
PubChem CID	9838802

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 3
TPSA	43.7 Å²
Synonyms	O-demethyltramadol hydrochloride, Phenol, 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, hydrochloride, cis-, Phenol, 3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, hydrochloride, rel-, 3-((1R,2R)-2-((Dimethylamino)methyl)-1-hydroxycyclohexyl)phenol hydrochloride, 3-[(1R,2R)-2-[(Dimethylamino)methyl]-1-hydroxycyclohexyl]phenol Hydrochloride, O-Desmethyl-cis-tramadol.HCl, Phenol, 3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-, hydrochloride (1:1), (1RS,2RS)-2-[(Dimethylamino)methyl]-1-(3-hydroxyphenyl)cyclohexanol Hydrochloride, Desmethyltramadol HCl, O-Desmethyl-cis-tramadol HCl

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H336May cause drowsiness or dizziness
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P271, P273, P301 + P316, P304 + P340, P319, P321, P330, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Tramadol Hydrochloride?

The CAS Registry Number of O-Desmethyl Tramadol Hydrochloride is 185453-02-5. It is also known as O-demethyltramadol hydrochloride, Phenol, 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, hydrochloride, cis-, Phenol, 3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, hydrochloride, rel-.

What is the molecular formula and molecular weight of O-Desmethyl Tramadol Hydrochloride?

O-Desmethyl Tramadol Hydrochloride has the molecular formula C15H24ClNO2 and a molecular weight of 285.81 g/mol.

What is O-Desmethyl Tramadol Hydrochloride used for?

O-Desmethyl Tramadol Hydrochloride is supplied as a characterised reference material related to Tramadol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Tramadol Hydrochloride can I order?

We supply O-Desmethyl Tramadol Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Tramadol Hydrochloride?

Yes. Every lot of O-Desmethyl Tramadol Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Tramadol Hydrochloride be shipped internationally?

Yes. O-Desmethyl Tramadol Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.