Nilotinib Impurity B

Name: Nilotinib Impurity B
Brand: Vaqora Chemicals
SKU: VQ-005363

About Nilotinib Impurity B

Nilotinib Impurity B (CAS 18595-18-1) is an impurity of Nilotinib offered by Vaqora Chemicals. Formula C9H11NO2, molecular weight 165.19 g/mol. The IUPAC name is methyl 3-amino-4-methylbenzoate. Common synonyms include 3-Amino-p-toluic Acid Methyl Ester and 2-Methyl-5-methoxycarbonylaniline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Nilotinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib Impurity B
Catalogue No.	VQ-005363
CAS Number	18595-18-1
IUPAC name	methyl 3-amino-4-methylbenzoate
Molecular formula	C₉H₁₁NO₂
Molecular weight	165.19 g/mol
Exact mass	165.079
Grade	Reference Standard
HSN code	38229090
InChIKey	YEPWCJHMSVABPQ-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)OC)N
PubChem CID	337778

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 3
TPSA	52.3 Å²
Synonyms	3-Amino-p-toluic Acid Methyl Ester, 2-Methyl-5-methoxycarbonylaniline, 3-Amino-4-methylbenzoic Acid Methyl Ester, Benzoic acid, 3-amino-4-methyl-, methyl ester, Methyl 3-Amino-4-Methyl-Benzoate, Methyl 3-amino-p-toluate, Nilotinib EP impurity B, Methyl 4-methyl-3-aminobenzoate, Methyl 3-Amion-4-Methylbenzoate, 3-amino-4-methyl-benzoic acid methyl ester, Nilotinib impurity B CRS, 3-amino-4-methyl-benzoic ac

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib Impurity B?

The CAS Registry Number of Nilotinib Impurity B is 18595-18-1. It is also known as 3-Amino-p-toluic Acid Methyl Ester, 2-Methyl-5-methoxycarbonylaniline, 3-Amino-4-methylbenzoic Acid Methyl Ester.

What is the molecular formula and molecular weight of Nilotinib Impurity B?

Nilotinib Impurity B has the molecular formula C9H11NO2 and a molecular weight of 165.19 g/mol. Its IUPAC name is methyl 3-amino-4-methylbenzoate.

What is Nilotinib Impurity B used for?

Nilotinib Impurity B is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib Impurity B can I order?

We supply Nilotinib Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib Impurity B?

Yes. Every lot of Nilotinib Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib Impurity B be shipped internationally?

Yes. Nilotinib Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.