(R)-1-Boc-3-Aminopiperidine

Name: (R)-1-Boc-3-Aminopiperidine
Brand: Vaqora Chemicals
SKU: VQ-012777

About (R)-1-Boc-3-Aminopiperidine

Listed under CAS 188111-79-7, (R)-1-Boc-3-Aminopiperidine is a process intermediate or related compound of Linagliptin available from Vaqora Chemicals. Its molecular formula is C10H20N2O2 and its molecular weight is 200.28 g/mol. The IUPAC name is tert-butyl (3R)-3-aminopiperidine-1-carboxylate. Common synonyms include (R)-(-)-3-Amino-1-Boc-piperidine and (R)-1-tert-Butoxycarbonyl-3-aminopiperidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Linagliptin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-1-Boc-3-Aminopiperidine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-1-Boc-3-Aminopiperidine
Catalogue No.	VQ-012777
CAS Number	188111-79-7
Other CAS	1956437-15-2
IUPAC name	tert-butyl (3R)-3-aminopiperidine-1-carboxylate
Molecular formula	C₁₀H₂₀N₂O₂
Molecular weight	200.28 g/mol
Exact mass	200.1525
Grade	Reference Standard
HSN code	2933
InChIKey	AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES	CC(C)(C)OC(=O)N1CCC[C@H](C1)N
PubChem CID	1501974

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 3
TPSA	55.6 Å²
Synonyms	(R)-(-)-3-Amino-1-Boc-piperidine, (R)-1-tert-Butoxycarbonyl-3-aminopiperidine, (R)-3-Amino-1-Boc-piperidine, (R)-3-Amino-1-N-tert-butoxycarbonylpiperidine, (R)-3-Amino-1-tert-butoxycarbonylpiperidine, (R)-3-Aminopiperidine-1-carboxylic acid tert-butyl ester, (R)-tert-Butyl 3-aminopiperidine-1-carboxylate, 3-(R)-Aminopiperidine-1-carboxylic acid tert-butyl ester, 3-Aminopiperidine-1-carboxylic acid (R)-tert-butyl ester, tert-Butyl (3R)-3-[(pyridin-2-yl)amido]piperidine-1-carboxylate, tert-Butyl (R)-3-aminopiperidine-1-carboxylate, (R)-3-Amino-1-N-BOC-piperidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-1-Boc-3-Aminopiperidine?

The CAS Registry Number of (R)-1-Boc-3-Aminopiperidine is 188111-79-7. It is also known as (R)-(-)-3-Amino-1-Boc-piperidine, (R)-1-tert-Butoxycarbonyl-3-aminopiperidine, (R)-3-Amino-1-Boc-piperidine.

What is the molecular formula and molecular weight of (R)-1-Boc-3-Aminopiperidine?

(R)-1-Boc-3-Aminopiperidine has the molecular formula C10H20N2O2 and a molecular weight of 200.28 g/mol. Its IUPAC name is tert-butyl (3R)-3-aminopiperidine-1-carboxylate.

What is (R)-1-Boc-3-Aminopiperidine used for?

(R)-1-Boc-3-Aminopiperidine is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-1-Boc-3-Aminopiperidine can I order?

We supply (R)-1-Boc-3-Aminopiperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-1-Boc-3-Aminopiperidine?

Yes. Every lot of (R)-1-Boc-3-Aminopiperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-1-Boc-3-Aminopiperidine be shipped internationally?

Yes. (R)-1-Boc-3-Aminopiperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.