21-Deoxy Cortisone

Name: 21-Deoxy Cortisone
Brand: Vaqora Chemicals
SKU: VQ-025087

About 21-Deoxy Cortisone

21-Deoxy Cortisone (CAS 1882-82-2) is an impurity of Cortisone offered by Vaqora Chemicals. Formula C21H28O4, molecular weight 344.4 g/mol. It is also known as 17-Hydroxypregn-4-ene-3,11,20-trione or 17-alpha-Hydroxypregn-4-ene-3,11,20-trione.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Cortisone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 21-Deoxy Cortisone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cortisone

View every impurity, metabolite and intermediate we list for Cortisone.

Cortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Deoxy Cortisone
Catalogue No.	VQ-025087
CAS Number	1882-82-2
IUPAC name	(8S,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Molecular formula	C₂₁H₂₈O₄
Molecular weight	344.4 g/mol
Exact mass	344.1988
Grade	Reference Standard
HSN code	38229090
InChIKey	PUKLDDOGISCFCP-JSQCKWNTSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID	102178

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	71.4 Å²
Synonyms	17-Hydroxypregn-4-ene-3,11,20-trione, 17-alpha-Hydroxypregn-4-ene-3,11,20-trione, 4-Pregnen-17alpha-ol-3,11,20-trione, deoxycortisone, 21-Desoxycortisone, 17a-hydroxy-4-pregnen-3,11,20-trione, 17a-Hydroxypregn-4-ene-3,11,20-trione, 6-Pregn-4-en-17a-ol-3,11,20-trione, 17alpha-Hydroxypregn-4-ene-3,11,20-trione, Pregn-4-ene-3,11,20-trione, 17-hydroxy-

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Deoxy Cortisone?

The CAS Registry Number of 21-Deoxy Cortisone is 1882-82-2. It is also known as 17-Hydroxypregn-4-ene-3,11,20-trione, 17-alpha-Hydroxypregn-4-ene-3,11,20-trione, 4-Pregnen-17alpha-ol-3,11,20-trione.

What is the molecular formula and molecular weight of 21-Deoxy Cortisone?

21-Deoxy Cortisone has the molecular formula C21H28O4 and a molecular weight of 344.4 g/mol. Its IUPAC name is (8S,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione.

What is 21-Deoxy Cortisone used for?

21-Deoxy Cortisone is supplied as a characterised reference material related to Cortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Deoxy Cortisone can I order?

We supply 21-Deoxy Cortisone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Deoxy Cortisone?

Yes. Every lot of 21-Deoxy Cortisone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Deoxy Cortisone be shipped internationally?

Yes. 21-Deoxy Cortisone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.