Liothyronine EP Impurity B (Dihydrate Salt)

Name: Liothyronine EP Impurity B (Dihydrate Salt)
Brand: Vaqora Chemicals
SKU: VQ-006488

About Liothyronine EP Impurity B (Dihydrate Salt)

Liothyronine EP Impurity B (Dihydrate Salt) (CAS 18835-59-1) is a pharmacopeial impurity of Liothyronine offered by Vaqora Chemicals. With the molecular formula C9H13I2NO5, it has a molar mass of 469.01 g/mol. Systematically, it is named (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid. Dihydrate. Alternative names: 3,5-Diiodo-L-tyrosine dihydrate and Diiodotyrosine Dihydrate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Liothyronine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Liothyronine EP Impurity B (Dihydrate Salt) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Liothyronine

View every impurity, metabolite and intermediate we list for Liothyronine.

Liothyronine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Liothyronine EP Impurity B (Dihydrate Salt)
Catalogue No.	VQ-006488
CAS Number	18835-59-1
IUPAC name	(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid;dihydrate
Molecular formula	C₉H₁₃I₂NO₅
Molecular weight	469.01 g/mol
Exact mass	468.8883
Grade	Reference Standard
HSN code	38229090
InChIKey	YWAGQOOMOOUEGY-KLXURFKVSA-N
SMILES	C1=C(C=C(C(=C1I)O)I)C[C@@H](C(=O)O)N.O.O
PubChem CID	2724330

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 6
TPSA	85.6 Å²
Synonyms	(2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate, (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate, 3,5-Diiodo-L-tyrosine Dihydrate, Diiodotyrosine Dihydrate, L-Tyrosine, 3,5-diiodo-, hydrate (1:2), 3,5-Diiodo-4-Hydroxy-beta-Phenylalanine, 3,5-Diiodo-L-tyrosinedihydrate, 3,5-Dijodtyrosindihydrat, (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoicaciddihydrate, Iodogorgoic acid, apothyrin, jodgorgon, 3,5-Diiodo-L-tyrosine--water (1/2)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Liothyronine EP Impurity B (Dihydrate Salt)?

The CAS Registry Number of Liothyronine EP Impurity B (Dihydrate Salt) is 18835-59-1. It is also known as (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate, (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate, 3,5-Diiodo-L-tyrosine Dihydrate.

What is the molecular formula and molecular weight of Liothyronine EP Impurity B (Dihydrate Salt)?

Liothyronine EP Impurity B (Dihydrate Salt) has the molecular formula C9H13I2NO5 and a molecular weight of 469.01 g/mol.

What is Liothyronine EP Impurity B (Dihydrate Salt) used for?

Liothyronine EP Impurity B (Dihydrate Salt) is supplied as a characterised reference material related to Liothyronine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Liothyronine EP Impurity B (Dihydrate Salt) can I order?

We supply Liothyronine EP Impurity B (Dihydrate Salt) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Liothyronine EP Impurity B (Dihydrate Salt)?

Yes. Every lot of Liothyronine EP Impurity B (Dihydrate Salt) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Liothyronine EP Impurity B (Dihydrate Salt) be shipped internationally?

Yes. Liothyronine EP Impurity B (Dihydrate Salt) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.