Baricitinib Boronic acid intermediate

About Baricitinib Boronic acid intermediate

Baricitinib Boronic acid intermediate is an impurity of Baricitinib carrying the CAS registry number 1919837-50-5. The compound has the formula C16H25BN4O4S, corresponding to a molecular weight of 380.3 g/mol. Its systematic (IUPAC) name is 2-[1-ethylsulfonyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile. It is also known as Baricitinib-006.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Baricitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Baricitinib Boronic acid intermediate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Baricitinib

View every impurity, metabolite and intermediate we list for Baricitinib.

Baricitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Baricitinib Boronic acid intermediate
Catalogue No.	VQ-024498
CAS Number	1919837-50-5
IUPAC name	2-[1-ethylsulfonyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
Molecular formula	C₁₆H₂₅BN₄O₄S
Molecular weight	380.3 g/mol
Exact mass	380.169
Grade	Reference Standard
HSN code	38229090
InChIKey	LHTUCYOPHHHUEE-UHFFFAOYSA-N
SMILES	B1(OC(C(O1)(C)C)(C)C)C2=CN(N=C2)C3(CN(C3)S(=O)(=O)CC)CC#N
PubChem CID	125462124

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 7
TPSA	106 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Baricitinib Boronic acid intermediate?

The CAS Registry Number of Baricitinib Boronic acid intermediate is 1919837-50-5. It is also known as Baricitinib-006, 1-[3-(Cyanomethyl)-1-(ethylsulfonyl)-3-azetidinyl]pyrazole-4-boronic Acid Pinacol Ester.

What is the molecular formula and molecular weight of Baricitinib Boronic acid intermediate?

Baricitinib Boronic acid intermediate has the molecular formula C16H25BN4O4S and a molecular weight of 380.3 g/mol. Its IUPAC name is 2-[1-ethylsulfonyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile.

What is Baricitinib Boronic acid intermediate used for?

Baricitinib Boronic acid intermediate is supplied as a characterised reference material related to Baricitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Baricitinib Boronic acid intermediate can I order?

We supply Baricitinib Boronic acid intermediate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Baricitinib Boronic acid intermediate?

Yes. Every lot of Baricitinib Boronic acid intermediate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Baricitinib Boronic acid intermediate be shipped internationally?

Yes. We export Baricitinib Boronic acid intermediate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.