(R,R)-Hydroxy Bupropion

Name: (R,R)-Hydroxy Bupropion
Brand: Vaqora Chemicals
SKU: VQ-021026

About (R,R)-Hydroxy Bupropion

Vaqora Chemicals supplies (R,R)-Hydroxy Bupropion, a metabolite or degradation product of Bupropion registered under CAS number 192374-15-5. Its molecular formula is C13H18ClNO2 and its molecular weight is 255.74 g/mol. Its systematic (IUPAC) name is (2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol. Common synonyms include Bupropion Morpholinol (2R,3R)-Isomer.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bupropion, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R,R)-Hydroxy Bupropion is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,R)-Hydroxy Bupropion
Catalogue No.	VQ-021026
CAS Number	192374-15-5
IUPAC name	(2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Molecular formula	C₁₃H₁₈ClNO₂
Molecular weight	255.74 g/mol
Exact mass	255.1026
Grade	Reference Standard
HSN code	38229090
InChIKey	RCOBKSKAZMVBHT-RNCFNFMXSA-N
SMILES	C[C@@H]1[C@](OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O
PubChem CID	9943908

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²
Synonyms	Bupropion Morpholinol (2R,3R)-Isomer, (2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2R,3R)-, (-)-(2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, (2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol, rel-(2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, (+/-)-(2R,3R)-2-(3-chlorophenyl) -3,5,5-trimethyl-2-morpholinol, (+/-)-(2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,R)-Hydroxy Bupropion?

The CAS Registry Number of (R,R)-Hydroxy Bupropion is 192374-15-5. It is also known as Bupropion Morpholinol (2R,3R)-Isomer, (2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2R,3R)-.

What is the molecular formula and molecular weight of (R,R)-Hydroxy Bupropion?

(R,R)-Hydroxy Bupropion has the molecular formula C13H18ClNO2 and a molecular weight of 255.74 g/mol. Its IUPAC name is (2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol.

What is (R,R)-Hydroxy Bupropion used for?

(R,R)-Hydroxy Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,R)-Hydroxy Bupropion can I order?

We supply (R,R)-Hydroxy Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,R)-Hydroxy Bupropion?

Yes. Every lot of (R,R)-Hydroxy Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,R)-Hydroxy Bupropion be shipped internationally?

Yes. (R,R)-Hydroxy Bupropion is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.