Pemetrexed Impurity 19

About Pemetrexed Impurity 19

Pemetrexed Impurity 19 is an impurity of Pemetrexed carrying the CAS registry number 193281-05-9. The compound has the formula C19H21N5O7, corresponding to a molecular weight of 431.4 g/mol. Systematically, it is named (2S)-2-[[4-[3-(2,4-diamino-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid. Common synonyms include Pemetrexed Impurity 8.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Pemetrexed impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Pemetrexed Impurity 19 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Impurity 19
Catalogue No.	VQ-041372
CAS Number	193281-05-9
IUPAC name	(2S)-2-[[4-[3-(2,4-diamino-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid
Molecular formula	C₁₉H₂₁N₅O₇
Molecular weight	431.4 g/mol
Exact mass	431.1441
Grade	Reference Standard
HSN code	38229090
InChIKey	GQMLDZYRTDSOMZ-NSHDSACASA-N
SMILES	C1=CC(=CC=C1CCC(=O)C2=C(N=C(NC2=O)N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	136703979

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	6 / 9
TPSA	214 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Impurity 19?

The CAS Registry Number of Pemetrexed Impurity 19 is 193281-05-9. It is also known as Pemetrexed Impurity 8, N-[4-[3-(2,4-Diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic acid.

What is the molecular formula and molecular weight of Pemetrexed Impurity 19?

Pemetrexed Impurity 19 has the molecular formula C19H21N5O7 and a molecular weight of 431.4 g/mol. Its IUPAC name is (2S)-2-[[4-[3-(2,4-diamino-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid.

What is Pemetrexed Impurity 19 used for?

Pemetrexed Impurity 19 is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Impurity 19 can I order?

We supply Pemetrexed Impurity 19 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Impurity 19?

Yes. Every lot of Pemetrexed Impurity 19 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Impurity 19 be shipped internationally?

Yes. We export Pemetrexed Impurity 19 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.