Dolutegravir Hydroxy Impurity

Name: Dolutegravir Hydroxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-004813

About Dolutegravir Hydroxy Impurity

Vaqora Chemicals supplies Dolutegravir Hydroxy Impurity, an impurity of Dolutegravir registered under CAS number 1973402-05-9 with a typical assay of 85%. Formula C20H19F2N3O5, molecular weight 419.4 g/mol. Alternative names: Dolutegravir Ring Open Impurity and 2-a]pyrazine-7-carboxamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Dolutegravir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Dolutegravir Hydroxy Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	Dolutegravir Hydroxy Impurity
Catalogue No.	VQ-004813
CAS Number	1973402-05-9
IUPAC name	N-[(2,4-difluorophenyl)methyl]-9-hydroxy-2-[(2R)-4-hydroxybutan-2-yl]-1,8-dioxopyrido[1,2-a]pyrazine-7-carboxamide
Molecular formula	C₂₀H₁₉F₂N₃O₅
Molecular weight	419.4 g/mol
Exact mass	419.1293
Grade	Reference Standard
Purity / assay	85%
HSN code	38229090
InChIKey	NQVIDZANHVWALI-LLVKDONJSA-N
SMILES	C[C@H](CCO)N1C=CN2C=C(C(=O)C(=C2C1=O)O)C(=O)NCC3=C(C=C(C=C3)F)F
PubChem CID	155923124

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 8
TPSA	110 Å²
Synonyms	Dolutegravir Ring Open Impurity, 2-a]pyrazine-7-carboxamide, Dolutegravir impurity 3, Dolutegravir Impurity 51, Dolutegravir Impurity 11, Dolutegravir Impurity A

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dolutegravir Hydroxy Impurity?

The CAS Registry Number of Dolutegravir Hydroxy Impurity is 1973402-05-9. It is also known as Dolutegravir Ring Open Impurity, 2-a]pyrazine-7-carboxamide, Dolutegravir impurity 3.

What is the molecular formula and molecular weight of Dolutegravir Hydroxy Impurity?

Dolutegravir Hydroxy Impurity has the molecular formula C20H19F2N3O5 and a molecular weight of 419.4 g/mol. Its IUPAC name is N-[(2,4-difluorophenyl)methyl]-9-hydroxy-2-[(2R)-4-hydroxybutan-2-yl]-1,8-dioxopyrido[1,2-a]pyrazine-7-carboxamide.

What is Dolutegravir Hydroxy Impurity used for?

Dolutegravir Hydroxy Impurity is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dolutegravir Hydroxy Impurity can I order?

We supply Dolutegravir Hydroxy Impurity in Reference Standard (85%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dolutegravir Hydroxy Impurity?

Yes. Every lot of Dolutegravir Hydroxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dolutegravir Hydroxy Impurity be shipped internationally?

Yes. We export Dolutegravir Hydroxy Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.