N-Acetyl-D-leucine

Name: N-Acetyl-D-leucine
Brand: Vaqora Chemicals
SKU: VQ-050882

About N-Acetyl-D-leucine

Vaqora Chemicals supplies N-Acetyl-D-leucine, a process intermediate or related compound of Leucine registered under CAS number 19764-30-8. Its molecular formula is C8H15NO3 and its molecular weight is 173.21 g/mol. Its systematic (IUPAC) name is (2R)-2-acetamido-4-methylpentanoic acid. Alternative names: Ac-D-Leu-OH and Acetylleucine, D-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Leucine, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Acetyl-D-leucine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Leucine

View every impurity, metabolite and intermediate we list for Leucine.

Leucine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl-D-leucine
Catalogue No.	VQ-050882
CAS Number	19764-30-8
IUPAC name	(2R)-2-acetamido-4-methylpentanoic acid
Molecular formula	C₈H₁₅NO₃
Molecular weight	173.21 g/mol
Exact mass	173.1052
InChIKey	WXNXCEHXYPACJF-SSDOTTSWSA-N
SMILES	CC(C)C[C@H](C(=O)O)NC(=O)C
PubChem CID	1241420

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 3
TPSA	66.4 Å²
Synonyms	Ac-D-Leu-OH, Acetylleucine, D-, Leucine, N-acetyl-, D-, (R)-acetylleucine, N-acetyl-D-Leu, D-acetylleucine, D-leucine, N-acetyl-, N-Acetyl-R-leucine, acetyl-d-leucine, (R)-2-acetamido-4-methylpentanoic acid, Acetylleucine, (R)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl-D-leucine?

The CAS Registry Number of N-Acetyl-D-leucine is 19764-30-8. It is also known as Ac-D-Leu-OH, Acetylleucine, D-, Leucine, N-acetyl-, D-.

What is the molecular formula and molecular weight of N-Acetyl-D-leucine?

N-Acetyl-D-leucine has the molecular formula C8H15NO3 and a molecular weight of 173.21 g/mol. Its IUPAC name is (2R)-2-acetamido-4-methylpentanoic acid.

What is N-Acetyl-D-leucine used for?

N-Acetyl-D-leucine is supplied as a characterised reference material related to Leucine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl-D-leucine can I order?

We supply N-Acetyl-D-leucine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl-D-leucine?

Yes. Every lot of N-Acetyl-D-leucine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl-D-leucine be shipped internationally?

Yes. N-Acetyl-D-leucine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.