(S)-Duloxetine Phthalamide

About (S)-Duloxetine Phthalamide

(S)-Duloxetine Phthalamide is an impurity of Duloxetine carrying the CAS registry number 199191-67-8. The compound has the formula C26H23NO4S, corresponding to a molecular weight of 445.5 g/mol. Its systematic (IUPAC) name is 2-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]carbamoyl]benzoic acid. Alternative names: Duloxetine Pthalimide and Duloxetine phthalimide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Duloxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (S)-Duloxetine Phthalamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Duloxetine Phthalamide
Catalogue No.	VQ-022465
CAS Number	199191-67-8
IUPAC name	2-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]carbamoyl]benzoic acid
Molecular formula	C₂₆H₂₃NO₄S
Molecular weight	445.5 g/mol
Exact mass	445.1348
Grade	Reference Standard
HSN code	38229090
InChIKey	QYWSULHSCQVWPV-QHCPKHFHSA-N
SMILES	CN(CC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32)C(=O)C4=CC=CC=C4C(=O)O
PubChem CID	71777250

Physical properties
Physical form	Solid
LogP (XLogP3)	5.4
H-bond donors / acceptors	1 / 5
TPSA	95.1 Å²
Synonyms	Duloxetine Pthalimide, Duloxetine phthalimide, Duloxetine phthalamide, (S)-Duloxetine Phtalamide, (S)-2-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamoyl)benzoic acid, 2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid, 2-[methyl-[(3S)-3-(1-naphthyloxy)-3-(2-thienyl)propyl]carbamoyl]benzoic acid, 2-{Methyl[(3S)-3-[(naphthalen-1-yl)oxy]-3-(thiophen-2-yl)propyl]carbamoyl}benzoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Duloxetine Phthalamide?

The CAS Registry Number of (S)-Duloxetine Phthalamide is 199191-67-8. It is also known as Duloxetine Pthalimide, Duloxetine phthalimide, Duloxetine phthalamide.

What is the molecular formula and molecular weight of (S)-Duloxetine Phthalamide?

(S)-Duloxetine Phthalamide has the molecular formula C26H23NO4S and a molecular weight of 445.5 g/mol. Its IUPAC name is 2-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]carbamoyl]benzoic acid.

What is (S)-Duloxetine Phthalamide used for?

(S)-Duloxetine Phthalamide is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Duloxetine Phthalamide can I order?

We supply (S)-Duloxetine Phthalamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Duloxetine Phthalamide?

Yes. Every lot of (S)-Duloxetine Phthalamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Duloxetine Phthalamide be shipped internationally?

Yes. We export (S)-Duloxetine Phthalamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.