Methyl Oxindole-5-carboxylate

Name: Methyl Oxindole-5-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-049251

About Methyl Oxindole-5-carboxylate

Vaqora Chemicals supplies Methyl Oxindole-5-carboxylate, an impurity of Nintedanib registered under CAS number 199328-10-4. Its molecular formula is C10H9NO3 and its molecular weight is 191.18 g/mol. Systematically, it is named methyl 2-oxo-1,3-dihydroindole-5-carboxylate. It is also known as Methyl-2-oxoindoline-5-carboxylate or Methyl 2-Oxoindoline-5-carboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl Oxindole-5-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl Oxindole-5-carboxylate
Catalogue No.	VQ-049251
CAS Number	199328-10-4
IUPAC name	methyl 2-oxo-1,3-dihydroindole-5-carboxylate
Molecular formula	C₁₀H₉NO₃
Molecular weight	191.18 g/mol
Exact mass	191.0582
Grade	Reference Standard
HSN code	38229090
InChIKey	CYBPPDZFRDSSME-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC2=C(C=C1)NC(=O)C2
PubChem CID	2773516

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 3
TPSA	55.4 Å²
Synonyms	Methyl-2-oxoindoline-5-carboxylate, Methyl 2,3-dihydro-2-oxo-1H-indole-5-carboxylate, Methyl 2-Oxoindoline-5-carboxylate, Methyl 2-oxindole-5-carboxylate, methyl 2-oxo-2,3-dihydro-1H-indole-5-carboxylate, 1H-Indole-5-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester, methyl 2-oxo-5-indolinecarboxylate, 5-methoxycarbonyloxindole, 5-Methoxycarbonyl-2-oxindole, methyl-2-oxindole-5-carboxylate, methyl 2-hydroxy-1H-indole-5-carboxylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl Oxindole-5-carboxylate?

The CAS Registry Number of Methyl Oxindole-5-carboxylate is 199328-10-4. It is also known as Methyl-2-oxoindoline-5-carboxylate, Methyl 2,3-dihydro-2-oxo-1H-indole-5-carboxylate, Methyl 2-Oxoindoline-5-carboxylate.

What is the molecular formula and molecular weight of Methyl Oxindole-5-carboxylate?

Methyl Oxindole-5-carboxylate has the molecular formula C10H9NO3 and a molecular weight of 191.18 g/mol. Its IUPAC name is methyl 2-oxo-1,3-dihydroindole-5-carboxylate.

What is Methyl Oxindole-5-carboxylate used for?

Methyl Oxindole-5-carboxylate is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl Oxindole-5-carboxylate can I order?

We supply Methyl Oxindole-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl Oxindole-5-carboxylate?

Yes. Every lot of Methyl Oxindole-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl Oxindole-5-carboxylate be shipped internationally?

Yes. Methyl Oxindole-5-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.