Glimepiride-d8

About Glimepiride-d8

Glimepiride-d8 is a stable isotope labelled analogue related to Glimepiride carrying the CAS registry number 2012598-49-9. With the molecular formula C24H34N4O5S, it has a molar mass of 498.7 g/mol. Common synonyms include TMID-0537.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Glimepiride-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Glimepiride

View every impurity, metabolite and intermediate we list for Glimepiride.

Glimepiride impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Glimepiride-d8
Catalogue No.	VQ-031005
CAS Number	2012598-49-9
IUPAC name	4-ethyl-3-methyl-5-oxo-N-[1,1,2,2-tetradeuterio-2-[2,3,5,6-tetradeuterio-4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2H-pyrrole-1-carboxamide
Molecular formula	C₂₄H₃₄N₄O₅S
Molecular weight	498.7 g/mol
Exact mass	498.2752
Grade	Reference Standard
HSN code	38229090
InChIKey	WIGIZIANZCJQQY-VRLZOOMQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C([2H])([2H])C([2H])([2H])NC(=O)N2CC(=C(C2=O)CC)C)[2H])[2H])S(=O)(=O)NC(=O)NC3CCC(CC3)C)[2H]
PubChem CID	171714228

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	3 / 5
TPSA	133 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Glimepiride-d8?

The CAS Registry Number of Glimepiride-d8 is 2012598-49-9. It is also known as TMID-0537.

What is the molecular formula and molecular weight of Glimepiride-d8?

Glimepiride-d8 has the molecular formula C24H34N4O5S and a molecular weight of 498.7 g/mol. Its IUPAC name is 4-ethyl-3-methyl-5-oxo-N-[1,1,2,2-tetradeuterio-2-[2,3,5,6-tetradeuterio-4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2H-pyrrole-1-carboxamide.

What is Glimepiride-d8 used for?

Glimepiride-d8 is supplied as a characterised reference material related to Glimepiride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Glimepiride-d8 can I order?

We supply Glimepiride-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Glimepiride-d8?

Yes. Every lot of Glimepiride-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Glimepiride-d8 be shipped internationally?

Yes. We export Glimepiride-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.