Tenofovir Disoproxil

About Tenofovir Disoproxil

Tenofovir Disoproxil is a process intermediate or related compound of Tenofovir carrying the CAS registry number 201341-05-1. The compound has the formula C19H30N5O10P, corresponding to a molecular weight of 519.4 g/mol. Common synonyms include Bis-POC-PMPA and Bis(POC)PMPA.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Tenofovir, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Tenofovir Disoproxil in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Tenofovir Disoproxil
Catalogue No.	VQ-013806
CAS Number	201341-05-1
IUPAC name	[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
Molecular formula	C₁₉H₃₀N₅O₁₀P
Molecular weight	519.4 g/mol
Exact mass	519.173
Grade	Reference Standard
HSN code	2933
InChIKey	JFVZFKDSXNQEJW-CQSZACIVSA-N
SMILES	C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C
PubChem CID	5481350

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 14
TPSA	185 Å²
Synonyms	Bis-POC-PMPA, Bis(POC)PMPA, (r)-bis(poc)pmpa, tenofovir bis(isopropyloxycarbonyloxymethyl) ester, 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine, 9-[(r)-2-[[bis[[(isopropoxycarbonyl)oxy]methoxy]phosphinyl]methoxy]propyl]adenine, tenofovir-disoproxil, Bis(isopropyloxymethylcarbonyl)PMPA, Viread(TM) (1:1 Fumarate salt), GS 4331-05 (1:1 Fumarate salt), [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tenofovir Disoproxil?

The CAS Registry Number of Tenofovir Disoproxil is 201341-05-1. It is also known as Bis-POC-PMPA, Bis(POC)PMPA, (r)-bis(poc)pmpa.

What is the molecular formula and molecular weight of Tenofovir Disoproxil?

Tenofovir Disoproxil has the molecular formula C19H30N5O10P and a molecular weight of 519.4 g/mol. Its IUPAC name is [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate.

What is Tenofovir Disoproxil used for?

Tenofovir Disoproxil is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tenofovir Disoproxil can I order?

We supply Tenofovir Disoproxil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tenofovir Disoproxil?

Yes. Every lot of Tenofovir Disoproxil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tenofovir Disoproxil be shipped internationally?

Yes. We export Tenofovir Disoproxil worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.